Skip to content
Research Article Open access CC BY 4.0

Adiposity, Atherogenic Index and Lipid Profile of Male Wistar Rats Administered with Kunun-Zaki

AYODELE Ifeoluwa Aderonke, OLANIYAN Adebola Oluwapolola, OLAYIWOLA Kehinde Olamide, Iyanda Ayobola Abolape

Asian Journal of Research in Biochemistry · pp. 23–31 · Published 7 Jul 2022

10.9734/ajrb/2022/v10i330225

Abstract

Aim: Kunun-zaki (KZ) is a highly refreshing local beverage that is commonly consumed both in urban and rural areas. The objective of the study was to investigate the effect of KZ on lipid profile and other markers of cardio-vascular risks in Wistar rats. Methods: Fourteen adult male Wistar rats (mean weight of 150 g) used for the study were randomly divided into 2 groups (Groups A & B) of 7 rats each. The experimental rats in Group A and B were administered daily with 5 mL of distilled water and kunun zaki respectively for a period of 2 weeks. All experimental animals were allowed access to standard feed and water ad libitum. Blood samples were collected and analyzed for total cholesterol (TC), triglyceride (TG), low density lipoprotein- cholesterol (LDL-C), high density lipoprotein- cholesterol (HDL-C), and very low density lipoprotein cholesterol (VLDL-C) using standard biochemical methods. The body mass index (BMI), atherogenic index, and adiposity index were also determined. Liver, kidney and heart were harvested and weighed to determine organ weights. The results were statistically analyzed using Student’s 't’test and by Pearson’s correlation coefficient. All values were presented as mean ± standard error of mean.  P< 0.05 was considered significant. Results: While TC, LDL-C, HDL-C concentrations were not significantly different, both TG and VLDL-C concentrations in KZ administered rats were significantly higher compared with control. BMI, antherogenic index and adiposity were not significantly different also when both groups were compared. Conclusion: the results of the study indicate that kunun-zaki does cause modulatory elevation in lipid profile.

Kunun-zaki atherogenic index adiposity index lipid profile body mass index

References (17)

  1. 1 Estimation of the Concentration of Low-Density Lipoprotein Cholesterol in Plasma, Without Use of the Preparative Ultracentrifuge [DOI]
  2. 2 The plasma parameter log (TG/HDL-C) as an atherogenic index: correlation with lipoprotein particle size and esterification rate inapob-lipoprotein-depleted plasma (FERHDL) [DOI]
  3. 3 Atherogenic index of plasma as useful predictor of cardiovascular risk among postmenopausal women in Enugu, Nigeria.
  4. 4 Long-term sucrose solution consumption causes metabolic alterations and affects hepatic oxidative stress in wistar rats [DOI]
  5. 5 Hypolipidemic Effect of Black Pepper (Piper nigrum Linn.) in Rats Fed High Fat Diet [DOI]
  6. 6 Nature of Carbohydrates and Proteins in Three Pearl Millet Varieties Varying in Processing Characteristics and Kernel Texture [DOI]
  7. 7 Lipid profile and plasma antioxidant status in sweet carbonated beverage-induced metabolic syndrome in rat [DOI]
  8. 8 Beneficial Effect of Moderate Exercise in Kidney of Rat after Chronic Consumption of Cola Drinks [DOI]
  9. 9 Nutrient and sensory qualities of kunun zaki from different saccharification agents [DOI]
  10. 10 Exploring the Role of Grandparents in the Lives of Teenage Learners [DOI]
  11. 11 The correction of the metabolic parameters of msg-induced obesity in rats by 2-[4-(benzyloxy) phenoxy] acetic acid [DOI]
  12. 12 Assessment of Nutritional and Sensory Quality of Kunun Zaki - A Homemade Traditional Nigerian Beverage [DOI]
  13. 13 Effects of dietary garlic supplements on serum lipid profiles, LDL oxidation and weight gain in Western diet-fed rats [DOI]
  14. 14 The Effect of Ginger (Zingiber officinale) on Diet Induced Hyperlipidemia and Tissue Histology in Adult Female Wistar Rats: A Biochemical and Histopathological Study [DOI]
  15. 15 Raw Material Sustainability And The Performance Of Beverage Companies In Nigeria: A Study Of Intafact Beverages Onitsha [DOI]
  16. 16 Antioxidant activities and physicochemical properties of spiced Kunu beverage
  17. 17 [AIP--atherogenic index of plasma as a significant predictor of cardiovascular risk: from research to practice].

Cited by 0

No indexed citations yet.

Related research

Article metrics

Real usage data collected on this platform.

54

Page views

0

PDF downloads

21

Outbound clicks

0

Citations

Views over time

Views by country

Approximate, from request IP at view time — not citizenship or institution. Countries with fewer than 5 views are grouped as "Other".

Traffic sources

Referring site, by host.

Views and downloads exclude known bots/crawlers. Citations combines this platform's own DOI-resolved index with each external source's own reported total — see Cited by above for individually listed citing works. Last refreshed 0 seconds ago.