Abies webbiana Mediated Zinc Oxide Nanoparticles and Its Anti-inflammatory Activity

Abstract

Introduction: Green nanoparticle synthesis provides a number of advantages, including being environmentally friendly, taking less time, being less expensive, being more stable, and, most significantly, not requiring the use of harmful chemicals. Aim: The aim of the present study is to evaluate the anti-inflammatory activity of zinc oxide [ZnO] nanoparticles prepared using Abies webbiana extract. Materials and Methods: In this study, ZnO nanoparticles were characterised using ultraviolet-visible spectroscopy and inhibition of albumin denaturation assay using A. webbiana extract. Results: The biosynthesised ZnO particles exhibited potent anti-inflammatory activity to inhibit COX activity. ZnO nanoparticles can be developed as a novel medicine and can be used as an alternative to commercially available anti-inflammatory agents, thus reducing the major health problems. Conclusion: Using A.webbiana extract, the findings suggest a cost-effective and environmentally friendly production of ZnO nanoparticles. ZnO nanoparticles mediated by A. webbiana showed promising properties. More investigations are required to understand the properties of these nanoparticles, which have a wide range of medical and dental applications.