Role of Ayurveda-based Diet and Panchakarma Therapy on Quantitative Change in Coronary Atherosclerosis in Known CAD Assessed by Quantitative CT Coronary Angiography

Abstract

Background: Ischemic heart disease (IHD), a form of coronary artery disease(CAD), is one of the many cardiovascular diseases (CVDs) whose prevalence has reached epidemic proportions. The initial symptom of coronary artery disease is the development of atherosclerotic plaques in the coronary arteries. The greatest pharmaceutical strategy to manage atherosclerosis, however, still does not seem to appear to have widespread acceptance. Aim: To study the effect of restricted diet and Ischemia Reversal Program(IRP) panchakarma therapy on quantitative change in coronary atherosclerosis in known CAD assessed by quantitative CT coronary angiography. Methods: A total of 17 patients suffering from CAD were administrated IRP and restricted diet program for 90 days with regular follow-ups. Basic demographics, stress test, 2D echo, and computerized tomography (CT) coronary angiography test for all the patients were recorded before and after the treatment. Results: It was observed that 26.80% regression in Total atheroma volume(TAV), followed by  30.19% regression in high-density plaque, and 25.82% regression in low-density plaque was found in patients after the treatment. The total atheroma value is reduced by 160.7 mm (p<0.00). The baseline average weight of the patient decreased from 68.28 Kg to 63.97 Kg (p<0.02). Conclusion: IRP can help to stabilize the plaque for a longer lifespan in addition to decreasing the development of atherosclerosis when combined with a limited diet. The results of our study indicate that IRP Panchakarma therapy, in conjunction with restricted diet programs, can be used to treat individuals with coronary atherosclerosis who have known coronary artery disease as measured by quantitative CT angiography.