A Study of Controlled Release of Nano Particle Liquid Medicated Formulation using the RP-HPLC Method for Determination of Norethindrone into Dissolution Media
G. Lino Steffy Aster, M. Vijey Aanandhi, S. Rama Chandran
Journal of Pharmaceutical Research International · pp. 54–58 · Published 23 Mar 2022
10.9734/jpri/2022/v34i26B35983Abstract
The determination of norethindrone can be done using a variety of approaches. Both sophisticated and validation strategies are included in this technique. The purpose of this research was to improve and test a smooth overturned segment-excessive standard performance liquid chromatographic technique for assessing norethindrone in dissolution media. The column is a C18 column from Thermo Scientific (250 mm x 4.6mm ID, 5m length). Deionized water, acetonitrile (50:50, v/v), and 5 ml/l acetic acid was made up with the cellular phase. The detecting wavelength was changed to 245 nm and the glide rate was changed to 1.3 ml/minute. The basic approach that was utilised was to investigate norethindrone release from a nanoparticle liquid medication device (LMF). The results showed that the procedure has become easy, precise, and particular.
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