A Retrospective Study of Adipocytic Tumours Received at a Tertiary Care Center

Abstract

Introduction: Adipocytic tumours comprise a large proportion of the vast histomorphological spectrum of soft tissue tumours. They range from benign lipomas to malignant liposarcomas with an entire range of various histological sub-types in between. Liposarcomas account for 15-20% cases of soft tissue sarcomas diagnosed. They are characterized with a high recurrence rate, progression to higher grade with time making their correct and prompt diagnosis imperative. Aims: To analyze the clinicopathological profile of adipocytic tumours received at a tertiary care center over a period of three years. To determine the distribution of adipocytic tumours among different age groups and gender. To ascertain the most common site of occurrence/organ involved. To determine the most common histopathological subtypes among the benign and malignant adipocytic tumours. Study Design: Retrospective Descriptive study. Place and Duration of Study: Saveetha Medical College and Hospital, between July 2017-June 2020. Methodology: All cases of adipocytic tumours (218) inclusive of both resection and biopsy specimens received during the study period were included and their case records were accessed. The demographic details were obtained from the case records at the Medical Records Division and the histomorphological findings from the histopathology registers at the Department of Pathology. Results: In this study, from a total of 20,767 specimens received at our tertiary care center during the period of study, 1.05% (218) were adipocytic tumours, of which 97.25% (212) were benign lipomas and 2.75% (6) were malignant liposarcomas. Out of the total number of malignant tumours (1050) received during the period of study, 2.95% (31) were soft tissue sarcomas, out of which 19.35% (6) cases were liposarcomas. Among the liposarcomas received at our center, 50% (3) cases were well differentiated liposarcoma, 33.3% (2) cases were pleomorphic liposarcoma and 16.7% (1) cases were dedifferentiated liposarcoma.