Skip to content
Research Article Open access CC BY 3.0

A Facile Synthesis of 7-amino-1,3-diaryl-5-phenyl-2-thioxo-pyrano[2,3-d]pyrimidine-4(5H)-ones

Nimalini Moirangthem, Warjeet S. Laitonjam

Chemical Science International Journal · pp. 58–70 · Published 4 Jul 2011

10.9734/ACSJ/2011/345

Abstract

The reactions of arylidene derivatives such as ethylphenylmethylenemalononitrile 3a, ethylphenylmethylenecyanoacetate 3b and ethylphenylmethylenecyano-acetamide 3c with substituted thiobarbituric acids 2a-e in presence of NaOCH3 and MeOH afforded 7-amino-1,3-diaryl-5-phenyl-2-thioxo-pyrano[2,3-d]pyrimidin-4(5H)ones 4a-e and 5e by cyclocondensation.

Synthesis pyranopyrimidines thiobarbituric acids arylidenes

References (15)

  1. 1 Lanthanide Triflate Catalyzed Biginelli Reaction. One-Pot Synthesis of Dihydropyrimidinones under Solvent-Free Conditions [DOI]
  2. 2 Green Synthesis of Pyrano[2,3‐ d ]‐pyrimidine Derivatives in Ionic Liquids [DOI]
  3. 3 H14[NaP5W30O110] catalyzed one-pot three-component synthesis of dihydropyrano[2,3-c]pyrazole and pyrano[2,3-d]pyrimidine derivatives [DOI]
  4. 4 Microwave-Assisted Concise Total Syntheses of Quinazolinobenzodiazepine Alkaloids [DOI]
  5. 5 Synthesis of some A- and D-ring fused steroidal pyrazoles, isoxazoles and pyrimidines [DOI]
  6. 6 An efficient synthesis of novel pyrano[2,3-d]- and furopyrano[2,3-d]pyrimidines via indium-catalyzed multi-component domino reaction [DOI]
  7. 7 Convenient selective synthesis of pyrano[2,3-d]pyrimidines [DOI]
  8. 8 Synthesis of fused pyrazolo-, isoxazolo-, pyrimido-, and pyridopyrimidines [DOI]
  9. 9 An Easy Synthesis of Pyranopyrimidines [DOI]
  10. 10 A novel one step synthesis of pyrano (2,3-d) pyrimidines [DOI]
  11. 11 Colour in relation to chemical constitution of the organic and inorganic salts ofisonitroso-diphenyl-thiobarbituric acid and its higher homologues and analogues [DOI]
  12. 12 A Study on the Synthesis of 5, 7-Diaryl-1,2,3,4-tetrahydro-2, 4-dioxo-5H-pyrano [2,3-d]pyrimidines [DOI]
  13. 13 A selective synthesis for novel pyranodipyrimidines
  14. 14 Efficient solid-phase synthesis of 1,2,3-benzotriazin-4-ones with SynPhaseTM Lanterns [DOI]
  15. 15 ChemInform Abstract: A Novel Synthesis of Pyrano(2,3‐d)pyrimidine Derivatives [DOI]

Cited by 6

Ultrasound-assisted rapid synthesis of 2-aminopyrimidine and barbituric acid derivatives

Duygu Bayramoğlu, Gülbin Kurtay, M. Güllü · Synthetic Communications · 2020

HPLC purification technique: synthesis of unsymmetrical thiobarbituric acids

V. D. Deotale, Manish M. Katiya, M. G. Dhonde · Heliyon · 2019

Recent Developments in the Synthesis of Bicyclic Condensed Pyrimidinones

Rayees Ahmad Naikoo, Rupesh Kumar, Vipan Kumar · Current Organic Chemistry · 2022

Construction of Biologically Active Five- and Six-Membered Fused Ring Pyrimidine Derivatives from 1,3-Diarylthiobarbituric Acids (DTBA)

Warjeet S. Laitonjam, Nimalini Moirangthem · Strategies for the Synthesis of Heterocycles and Their Applications · 2023

Article metrics

Real usage data collected on this platform.

2

Page views

0

PDF downloads

0

Outbound clicks

6

Citations

Views over time

Views by country

Approximate, from request IP at view time — not citizenship or institution. Countries with fewer than 5 views are grouped as "Other".

Traffic sources

Referring site, by host.

Views and downloads exclude known bots/crawlers. Citations combines this platform's own DOI-resolved index with each external source's own reported total — see Cited by above for individually listed citing works. Last refreshed 0 seconds ago.