A Correlative Study of Endometrial Glycogen Content in Female Infertility

Abstract

Infertility is a global problem. It has been viewed as a discredit and social humiliation thrust upon healthy young adults. The present detects the glycogen content in the endometrial glands of infertile women in the age group of 18 -39 years. This study aimed to compare infertility and the glycogen content in the endometrial glands of fertile women of the same age group. The endometrium is the tissue of attention because it is the site for implantation of ovum. The current study was done to evaluate the glycogen content in the endometrium of infertile patients and compare it with that of fertile patients. This study was done on 60 cases and 20 controls. Our study showed that large masses of glycogen (++++) was seen in only 7 secretory endometria in infertile cases (14.9%) when compared to 14 secretory endometria infertile subjects (77.7%). Also, endometrial glycogen grading in the secretory phase in infertile patients showed glycogen depletion (Grade 0) in 13 cases (27.7%) whereas it was nil in the fertile group. Glycogen is an essential and straight source of nutrient for the primary concepts and also helps in the successful implantation of blastocyst and continuation of pregnancy.