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Research Article Open access CC BY 4.0

A Case of Age Related Macular Degeneration Responding to a Statin – Perspective for a New Treatment

Helmut Gohlke, Lutz L. Hansen

Journal of Advances in Medicine and Medical Research · pp. 1–6 · Published 4 Aug 2015

10.9734/BJMMR/2015/19135

Abstract

The newly started use of atorvastatin eliminated the need for further intravitreal injections of ranibizumab for 37 months in a case of wet form of age related macular degeneration(AMD). Repeated optical coherence tomographic examinations documented the absence of intra- or subretinal fluid. The known effects of statins on endothelial function might also improve retinal capillary endothelial function and reduce or eliminate fluid leakage into the intra- or subretinal space. This would intervene earlier in one important disease mechanism of AMD than the injection of anti-VEGF therapies. A randomized study is necessary to prove this hypothesis.

Age related macular degeneration (AMD) intravitreal injections atorvastatin ranibizumab bevacizumab subretinal fluid vascular endothelial growth factor (VEGF)

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