Maternal Seroprevalence of Hepatitis B Virus Serologic Markers among Attendees of a Secondary Health Facility in Maiduguri, Nigeria
S. O. Oyinloye, M. Osunkwo, B. Taki-Mohd, B. B. Ajayi, M. A. Lawan
Microbiology Research Journal International · pp. 1–7 · Published 30 Oct 2015
10.9734/BMRJ/2016/18201Abstract
The profile of four hepatitis B virus markers [Hepatitis B surface antigen (HBsAg), antibodies of the immunoglobulin M (IgM) class against the hepatitis B core antigen (IgM anti-HBc), Hepatitis B surface antibody (Anti-HBs) and Hepatitis B envelop antigen (HBeAg)] among pregnant women (n=91), with mean age of 25.96 years, were determined using Enzyme linked immunosorbent assay kit. A significant (p=0.00001) overall sero-prevalence of 8.79%, 36.26%, 6.59% and 7.65% were observed for HBsAg, Anti-HBs, IgM anti-HBc and HBeAg respectively. Forty seven point three percent were susceptible (HBsAg -Ve, IgM anti-HBc -ve and anti-HBs-ve) to hepatitis B virus infection. One of thirteen pregnant women tested positive for HBsAg and HBeAg; this portends high risk of transmission to the fetus. This result portrays the unreliability of using presence of HBsAg as the sole marker for hepatitis B virus infection, high susceptibility to hepatitis B virus infection and the risk of transmission of HBV to fetuses.
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S. Oyinloye, D. Bukbuk, F. Sanda · Journal of Advances in Medicine and Medical Research · 2019
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