Outcome of Azithromycin with Non-Surgical Periodontitis Therapy at Dental Hospital, University of Health Sciences, Lao PDR

Abstract

Objective: The study aimed to evaluate the effectiveness of Azithromycin as an adjunct to non-surgical periodontal therapy. Methods: This is a cross-sectional descriptive study. The subjects were divided into two equal groups (Group study and Group control). At baseline, patients received a full-mouth supra scaling with an ultrasonic scaler, scaling, and root planing in sites with probing depths >4 mm, and were placed on a systemic antibiotic regimen: Azithromycin 250 mg (Group study) and doxycycline 250 mg (Group control), all groups once a day for 5 days. The subjects were recalled at day 5, day 30, and day 90. Results: The comparison of the outcome of periodontitis treatment with Azithromycin 250 mg and doxycycline 250 mg, evaluated by plaque index and clinical attachment loss, showed significant differences between the groups. The clinical parameters were different from the baseline values. Conclusion: Azithromycin 250 mg with non-surgical periodontitis therapy was significant.