Bogdan A. Tretyakov, Svyatoslav Y. Gadomsky & Alexei A. Terentiev·Organics·2023
We describe a novel two-step approach for the synthesis of compounds with a hydroxyl-amide group (hydroxamic acids), which are widely known for their biological activity (histone deacetylase inhibitors, matrix metalloproteinases inhibitors and others). The first stage is the synt...
Sulfoxides and sulfinamides play important roles in the pharmaceutical industry, organic synthesis and fine chemicals. This review will demonstrate that, under catalysis by transition metals, β-sulfinyl esters, as nucleophilic reagents, react with a variety of electrophilic reage...
The photochemical reaction of N-methyl-1,2,4-triazoline-3,5-dione (MeTAD) with benzene is known to lead to a Diels–Alder cycloaddition product when conducted at low temperatures (i.e., <−60 °C). This reactivity has been exploited recently for novel synthetic applications. It w...
Rebecca Hermans, Max Van Hoof, Luc Van Meervelt & Wim Dehaen·Organics·2023
The Nenitzescu reaction is a condensation reaction between an enamine and a quinone, which can give rise to a wide variety of reaction products depending on the nature of the starting material and the reaction conditions. The most commonly observed products are 5-hydroxyindoles a...
Till Hauenschild & Dariush Hinderberger·Organics·2023
A new rapid iodination reagent, N1,N3,N5-tris[(2,4,6-trimethylpyridine)iodo(I)]-2,4,6-triphenyl-s-triazine trihexafluorophosphate, was synthesized in a modification of the established synthesis of 2,4,6-triiodo-3,5-dimethylphenol in the presence of bis(2,4,6-trimethylpyridine)iod...
In the present work, we report a simple synthetic strategy for fabricating ZnCuInS/ZnS–TPPS4 conjugates and study its cytotoxicity as a promising material for imaging and phototherapy applications. The quaternary QDs were synthesized using eco-friendly materials such as glutathio...
Cardanol, a waste from the food industry and widely produced (1 Mt/y), has been used as a chain stopper during the polycondensation of short oil alkyd resins in order to replace benzoic acid. Then, phosphorylated cardanol has been added in order to both reduce solvent content and...
Aleksandra N. Zhivchikova, Irina V. Klimovich, Maxim E. Sideltsev, Aly Elakshar, Artur T. Kapasharov, Alexander V. Akkuratov, Albert G. Nasibulin, Keith J. Stevenson & Marina M. Tepliakova·Organics·2023
Here, we present a synthesis of three novel conjugated block-copolymers (BCP) with general formula P3HT-bridge-TBO, where P3HT is a poly(3-hexyl)thiophene, TBO is a thiophene-benzothiadiazole block, and the bridge is composed of two fluorene units (FF) or two thiophenes (TT) or a...
Thia-Michael reactions between aliphatic and aromatic thiols and various Michael acceptors were performed under environmentally-friendly solvent-free conditions using Amberlyst® A21 as a recyclable heterogeneous catalyst to efficiently obtain the corresponding adducts in high yie...
Vishnu K. Omanakuttan, Alisha Valsan, Henning Hopf & Jubi John·Organics·2023
We have realized a Pd-catalyzed ring-opening of diazabicyclic olefins with 4-halo-1,3-dicarbonyl compounds. This reaction resulted in the formation of 3(2H)-furanone-appended hydrazino cyclopentenes. The reaction proceeds via the formation of a π-allylpalladium intermediate which...