Aims: Inflammation has been implicated in many disorders and currently available therapies elicit adverse effects. The coarse shrub of Calotropis procera has been used in folk medicine to treat several ailments such as asthma, rheumatism and also fever. The anti-inflammatory pote...
Open access
Research Article10.9734/JPRI/2018/42529
Vernonia amygdalina popularly called bitter leaf is used in traditional medicine to treat fever, malaria, diarrhoea, dysentery and diabetes. They serve as laxatives and fertility inducer. They are commonly used as vegetable. The effects of methanolic extract of Vernonia amygdalin...
Open access
Research Article10.9734/JPRI/2018/41908
Aim: This study investigated the acute toxicity (LD50) and antipsychotic potentials of ethanol leaf extract of Milicia excelsa (EME), hexane (HF), ethyl acetate (EAF), butanol (BF) and aqueous (AF) fractions in mice. Study Design: This study used experimental mice models predicti...
Open access
Research Article10.9734/JPRI/2018/42383
The present study was aimed at the in-vitro analysis of the antioxidant and antidiabetic potential of the methanol extracts of four perennial plants which are indigenous to Botswana and further to investigate whether their antihyperglycemic effects are working through the antioxi...
Open access
Research Article10.9734/JPRI/2018/42218
Background: Diclofenac is used as a potential analgesic for mild to moderately severe pain including migraine pain. However, the common side effect of this drug (drowsiness) becomes bothersome for patients taking diclofenac on regular basis in order to get rid of migraine pain. T...
Open access
Research Article10.9734/JPRI/2018/40988
The purpose of this study was to formulate and evaluate metoprolol tartrate (MT) loaded liposomes using factorial design. Preparation of niosomal drug delivery of MT increased its bioavailability which led to being better therapeutic effects, reduced the frequency of dosing and d...
Open access
Research Article10.9734/JPRI/2018/42068
Isaac Tabiri Henneh, Robertson Akrofi, Elvis Ofori Ameyaw, Daniels Konja, George Owusu, Bashiru Abane, Joseph Acquah-Mills, Fred Jonathan Edzeameh & Francis Tayman·Journal of Pharmaceutical Research International·2018
Aims: The stem bark of Sterculia setigera has been used in several African countries for the treatment of many inflammatory conditions. However, there is no scientific report to authenticate this usage. The current study, therefore, aims at assessing the in vitro and in vivo anti...
Open access
Research Article10.9734/JPRI/2018/42030
Objective: Ginseng is a plant which has high Antioxidant feature and contains Ginsenosides that has a high affectivity on testicle’s tissue. This study is done to increase the survival of germ cells and also to find out its effects on decreasing the restoration time of damaged te...
Open access
Research Article10.9734/JPRI/2018/42177
Aim: The present study aimed to investigate antidiabetic effects and to explore the underlying mechanism of S. chirata on neonatal-streptozotocin induced type 2 diabetic model (nSTZ-T2DM) rats. Methodology: Stem-barks were collected from local market, identified from Bangladesh N...
Open access
Research Article10.9734/JPRI/2018/41878
Aim: This study aims to evaluate the results of drug-induced sleep endoscopy(DISE) patients. Study Design: Retrospective study. Place and Duration of Study: Department of otorhinolaryngology between January 2018 and March 2018. Methodology: A total of 38 patients (32 males,6 fema...
Open access
Research Article10.9734/JPRI/2018/41559