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Journal of Pharmaceutical Research International

Published by SCIENCEDOMAIN international · ISSN (electronic) 2456-9119

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7,450

Articles indexed

84

2026 articles

7,450

Open access

20,711

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Articles (7450)

Ligand Based Drug Designing of Molecular Target PPARγ/AT1R through CDOCKER and ADMET Prediction

Zhi Jing, Ya-Ya Liu, Xiao-Yan Feng, Wen-Qing Jia, Jian-Wen Liu & Xian-Chao Cheng · Journal of Pharmaceutical Research International · 2018

Aims: The current research has shown that the complications of hypertensive diabetes have a great impact on the body. Telmisartan, an angiotensin II antagonist, has the dual role of antihypertensive and antidiabetics effects. This research aims to find a novel compound to treat h...

Open access Research Article 10.9734/JPRI/2018/43482

Evaluation of Methanolic Extract Induced Antinociceptive, Anti-pyretic and Anti-inflammatory Activity of Ficus hispida Leaves

S. M. Mushiur Rahman, Md. Rubel Haque, Md. Ashraful Zaman, Sohel Rana, Samiron Sana & Md. Tanjir Imam Hasan · Journal of Pharmaceutical Research International · 2018

Objective: Traditionally Ficus hispida is used as a palliative for pain, inflammation, diabetes, fever and neurological disorders. The present study set out to evaluate the antinociceptive, anti-pyretic and anti-inflammatory activity of the methanolic extract of Ficus hispida lea...

Open access Research Article 10.9734/JPRI/2018/41664

The Effect of Methyl Jasmonate on Monoterpene Composition of the Essential Oil in Shoot Cultures of Sautreja khuzistanica Jamzad

Fatemeh Farzi, Hamid Fahimi, Mozafar Sharifi & Amir Mousavi · Journal of Pharmaceutical Research International · 2018

Background and Objective: Numerous monoterpenes are present in the essential oil of Sautreja khuzistanica Jamzad. In this study, the effect of methyl jasmonate (MJ) applied in the LS medium of shoot cultures of S. khuzistanica on individual monoterpene percentages were evaluated....

Open access Research Article 10.9734/JPRI/2018/43472

Evaluation of the Cytotoxic Effect and PRRS Antiviral Activity of Glycyrrhizinic Acid in Aqueous Solution and with the Presence of Solid Lipid Nanoparticles

M. Z. Urbán-Morlán, S. E. Mendoza-Elvira, A. Jiménez-García de León, H. Ramírez-Mendoza, N. Mendoza-Muñoz, A. Ciprián-Carrasco & D. Quintanar-Guerrero · Journal of Pharmaceutical Research International · 2018

Aims: To study the effect of glycyrrhizinic acid (GA) solutions on uninfected and PRRS (Porcine Reproductive and Respiratory Syndrome) virus-infected cells in culture. An attempt of testing loaded nanoparticles with GA on cells was also explored. Study Design: Different concentra...

Open access Research Article 10.9734/JPRI/2018/44806

Studying the Effect of Local Solution of Clobetasol on Peritoneal Adhesion after Laparotomic Surgery in Rats

Soroush Noroozzadeh, Leila Ghafoor, Noshin Sadat Mosavi, Hamidreza Banafsheh, Amirhosein Matini & Seyed Alireza Morovaji · Journal of Pharmaceutical Research International · 2018

Background and Objective: Adhesion is an important complication of abdominal and pelvic surgery. Applying corticosteroids reduces vascular permeability and releasing of cytokines and chemotactic factors. The current study has examined the effect of clobetasol solution on intra-ab...

Open access Research Article 10.9734/JPRI/2018/45122

Controlled Release Binary and Ternary HPMC-HPC-Gelucire® 50/13 Hybrids Based Solid Dispersions of Indomethacin: In vitro Evaluation and In vivo Anti-inflammatory Studies

J. N. Reginald-Opara, K. C. Ofokansi, F. C. Kenechukwu, C. G. Nwaigwe & A. M. Nnogo · Journal of Pharmaceutical Research International · 2018

Aim: The aim of this study is to formulate and evaluate solid dispersions of indomethacin based on Gelucire 50/13, Hydroxylpropyl methylcellulose and/or Hydroxylpropyl cellulose hybrid binary or ternary system, with a view of enhancing oral bioavailability, sustaining drug releas...

Open access Research Article 10.9734/JPRI/2018/22643

Preoccupations and Worries in Women with Breast Cancer: A Qualitative Study

Shahrbanoo Ghahari, Raheleh Fallah, Leila Behnam, Mohammad Mazloumi Rad, Nazanin Farrokhi & Raoofeh Ghayoomi · Journal of Pharmaceutical Research International · 2018

Aims: As one of the most prevalent cancers among women, breast cancer can severely affect the patients psychologically. Worry and anxiety can be one of these effects. Hence, this study is conducted to evaluate the most important worries and preoccupations of women with breast can...

Open access Research Article 10.9734/JPRI/2018/40229

Formulation and Evaluation of Multi-particulate Drug Delivery System for Metformin Hydrochloride by Spray Drying Method

Abhay Shirode & Vilasrao Kadam · Journal of Pharmaceutical Research International · 2018

Diabetes mellitus is a serious emergency right now which is considered to be one of the major causes of death in all the nations. MET is considered to be one of the major medications to treat type two or insulin dependent diabetes mellitus. Though this process of oral administrat...

Open access Research Article 10.9734/JPRI/2018/39698

Isolation and Characterization of Cola acuminata Gum as a Potential Pharmaceutical Excipient

E. A. Bamigbola, M. A. Momoh & O. Ikebudu · Journal of Pharmaceutical Research International · 2018

Aim: Gums are polysaccharides composed of varying chemical compositions and a wide range of molecular weights. Appropriate evaluation of their physicochemical properties assists in determining their suitability as pharmaceutical excipients in the preparation of various dosage for...

Open access Research Article 10.9734/JPRI/2018/14526

Development and Evaluation of Papaya Peel Powder and Paste Incorporated Chapathis

C. S. Pavithra, S. Suchiritha Devi, W. Jessie Suneetha & Ch. V. Durga Rani · Journal of Pharmaceutical Research International · 2018

Consumption of natural bioactive compounds and dietary fibre offers health benefits and protection against lifestyle diseases. Papaya peel which is discarded waste contributes to environmental pollution, but it can be a good source of minerals, fibre and phenolic compounds with a...

Open access Research Article 10.9734/JPRI/2018/41384