Background: Cyclophosphamide (CYP), an alkylating chemotherapeutic agent, is widely used to treat several types of cancer. Its toxic effects are well-established and include hepatotoxicity, nephrotoxicity, and bone marrow suppression. Metformin (MET) is an anti-diabetic medicatio...
Open access
Research Article10.9734/jpri/2019/v30i230263
The objective of the current work was to develop and evaluate suppository dosage form in order to improve ranitidine bioavailability as a substitute to the oral administration. Suppocire (different grades), Witepsol W25 and polyethylene glycol (PEG) were used as suppository bases...
Open access
Research Article10.9734/jpri/2019/v30i130262
Background: Nickel is commonly used in industry, utensils and also present in cigarette. Over-exposure of nickel is known to cause several health complications including somatic and germinal cell injuries. Garlic (Allium sativum) being a spice has several pharmacological properti...
Open access
Research Article10.9734/jpri/2019/v30i130261
The present paper deals with the theoretical investigation of the combined influence of Coriolis force, electrical resistivity, electron plasma frequency and fine dust particles on the linear Jeans instability of gaseous plasma by using the generalized magneto-hydrodynamic fluid...
Open access
Research Article10.9734/iaarj/2019/v1i13
One of the proposed psychological treatments in hemodialysis patients is acceptance and commitment therapy. The acceptance and commitment therapy focuses on psychological flexibility and this occurs when a person consciously accepts his or her thoughts and feelings and shows a be...
Open access
Research Article10.9734/jpri/2019/v30i130260
Ogunlana Olubanke Olujoke, Oyebanji Olufisayo Grace, Ogunlana Oluseyi Ebenezer, Adekeye Bosede Temitope, Adeyemi Alaba Oladipupo, Titilope M. Dokunmu, Oluwakemi Anuoluwapo Rotimi, Solomon Oladapo Rotimi & E. Okwumabua Ogi·Journal of Pharmaceutical Research International·2019
Aim: The complications associated with diabetes and the new trend of using combination therapy in the management of the disease gave birth to this work, aimed at assessing the hepatotoxic and nephrotoxic effects of selected popularly used antidiabetic medications in type 2 diabet...
Open access
Research Article10.9734/jpri/2019/v30i130259
Introduction: Vitamin D deficiency has been rediscovered as a public health problem worldwide. It has been postulated that vitamin D deficiency explains a portion of the asthma epidemic. The purpose of this study was to assess the serum vitamin D levels in children with asthma as...
Open access
Research Article10.9734/jpri/2019/v30i130257
In this review article, several researchesabout genetic polymorphisms of Glutation –s transferase (GST) enzymes that may have an etiological role in breast cancer have been reviewed. Breast carcinoma is the most frequent malignancy in women and represents the second leading cause...
Open access
Research Article10.9734/jpri/2019/v29i630256
Multiple sclerosis is an autoimmune disease of the central nervous system with symptoms of neurodegenerative diseases. The symptoms vary depending on damage location. Some of the symptoms include cognitive disorders, anxiety and depression, visual impairment, respiratory, speech...
Open access
Research Article10.9734/jpri/2019/v29i630255
Background: The prevalence of intra-abdominal hypertension in ICU patients is about 50% and can be affected by changing the position of the patients. This study aimed to investigate the relationship between changing patient positions in bed with intra-abdominal pressure and mean...
Open access
Research Article10.9734/jpri/2019/v29i630254