Background: Diabetic neuropathy is very common and affects half of patients with either type 1 or type 2 diabetes mellitus. It is the leading cause of diabetes-related hospital admissions and nontraumatic amputations. Currently, the keys to management are maintaining blood glucos...
Open access
Research Article10.9734/jpri/2020/v32i3530977
Background: Glucocorticoids exert a wide range of physiological effects. They effectively control various inflammatory and autoimmune diseases and play an important role in organ transplantation. Glucocorticoids are associated with unfavorable side effects that restrict their ut...
Open access
Research Article10.9734/jpri/2020/v32i3530979
Vitamin D is a well-known steroid hormone that plays an important role in controlling bone levels of calcium, phosphorus, and overall mineralization. Several animal and human studies indicate that vitamin D hypovitaminosis may be linked to an increased risk of developing Alzheime...
Open access
Research Article10.9734/jpri/2020/v32i3530982
Nermina Ziga Smajic, Selma Skrbo, Naida Omerovic, Kemal Duric, Mirza Dedic, Anela Hadzifejzovic Trnka, Belma Pehlivanovic, Dina Lagumdzija & Fahir Becic·Journal of Pharmaceutical Research International·2020
Hyperuricemia is a potential marker of cardiovascular diseases, and its relation to hypertension and arteriosclerosis, as well as the outcomes of certain cardiovascular events, is interesting. The research was carried out a sample of 50 subjects of both sexes, who were either on...
Open access
Research Article10.9734/jpri/2020/v32i3530978
To develop and validate a RP-HPLC method for the determination of selected anti- leukemic drugs in bulk and pharmaceutical formulations using Design of experiments. Development of the chromatographic method is based on design of experiments (DOE) approach, utilizing two level ful...
Open access
Research Article10.9734/jpri/2020/v32i3530980
Introduction: The role of medicinal plants in meeting the healthcare needs of the populace, particularly in developing countries cannot be overemphasized. They provide holistic treatment and wellbeing due to a plethora of phytochemicals found in them. Among such is Tetrapleura te...
Open access
Research Article10.9734/jpri/2020/v32i3530981
Socioeconomic status and the education of mother plays important role in providing better health care and nutrition to children. To the best of our knowledge the major population of Pakistan belongs to middle class and identification of malnutrition in our setups may help the pol...
Open access
Research Article10.9734/jpri/2020/v32i3530983
Aims: This study aims to develop an efficient, and inexpensive transfection procedure using low cost polyethylenimine (PEI) as transfection reagent for overexpression of CYP2C9 in WRL 68 host cells. Introduction: Overexpression of CYP450 isozymes such as CYP2C9 has been a reliabl...
Open access
Research Article10.9734/jpri/2020/v32i3530975
Acne vulgaris is most common dermatological condition that affects more than 70% of teenagers and more than 10% of adults. The moisture content of human skin makes it appear young and primary function of moisturizer is to avoid the dehydration by preventing the moisture loss. Nat...
Open access
Research Article10.9734/jpri/2020/v32i3530976
Aim: Studied the critical factors in the design of an osmotic pump with metformin release rate constant at 4%/hr in diabetes mellitus within 24 hr. with the goal to reduce daily medications. Study Design: Experimental design 32 Methodology: In vitro drug release profiles for 24h....
Open access
Research Article10.9734/jpri/2020/v32i3530974