Aim: Iminothiazolidinones are one of the important classes of heterocyclic compounds and they occupied unique position in medicinal chemistry due to their wide range of biological and pharmaceutical properties. In view this potential activity, it has been planned to synthesize a...
Open access
Research Article10.9734/jpri/2021/v33i431169
Aim: Ramegepant is a novel molecule belongs to the class of calcitonin gene – related peptide (CGRP) receptor antagonist, which was developed for the prevention and treatment of migraine. Ramegepant was reported to act at the CGRP receptor with good oral bioavailability. The obje...
Open access
Research Article10.9734/jpri/2021/v33i431170
V. Sreedhar, L. Reddenna, T. Rajavardhana, J. Thippe Rudra, E. Pavan Kumar, M. Pramod Kumar, M. Kalyan Sai, T. Sivasaileela, Y. Yamini, B. Sreelekha, B. Nishkala & M. Mahesh·Journal of Pharmaceutical Research International·2021
There are diverse studies which afford evidences that risperidone is as effective as second generation antipsychotics in treating positive symptoms and more effective in treatment of negative symptoms. This study is intended to find the clinical efficacy and safety profile of lur...
Open access
Research Article10.9734/jpri/2021/v33i431167
The main objectives of this study were to qualitatively evaluate the profile of phytochemical constituents of Elytraria acaulis root (EAR) extracts. The dried powder of the roots of the plant was extracted with three different solvents namely petroleum ether, methanol and water,...
Open access
Research Article10.9734/jpri/2021/v33i431165
The major health problems affecting pregnant women in sub-Saharan African are anaemia, malaria and HIV. A case-control study aimed at determining the prevalence of malaria, anaemia and HIV status among women of reproductive age between 20-49 years attending General Hospital, Onit...
Open access
Research Article10.9734/jpri/2021/v33i431166
Background: Alzheimer’s disease (AD), a progressive neuropsychiatric disorder, is characterized by neuroinflammation, β-amyloid plaques and neurofibrillary tangles. It has been demonstrated that systemic inflammation and neuroinflammation caused by lipopolysaccharide (LPS) inject...
Open access
Research Article10.9734/jpri/2021/v33i331164
Ulcerative colitis (UC) is an inflammatory disease affecting the mucosa in the colon. Despite significant progress and expansion of the therapeutic armamentarium for UC, there are currently no curative medications available and some cases require colectomy. In this communication,...
Open access
Research Article10.9734/jpri/2021/v33i331160
Nisar Khan, Sajid Ali, Zuheeb Ahmed, Marvi Metlo, Asif Ali, Shaib Muhammad, Niaz Hussain Jamali, Arslan Ahmer, Salman Khan, Ata-ur- Rehman, Tahseen Ahmed & Shumaila Parveen Arain·Journal of Pharmaceutical Research International·2021
The main objective of this research was to evaluate the prescribing ratio of benzodiazepines in the patients suffering from a disease other than a mental disorder. A prospective cross-sectional study was conducted at 24 different community pharmacies and medical stores of Distric...
Open access
Research Article10.9734/jpri/2021/v33i331156
Aim: This study aims to describe the prescribing pattern of lactulose in the outpatient setting of a public hospital. Methodology: This is a cross-sectional study that was conducted in Alkharj city. Prescription data were collected retrospectively from electronic medical records...
Open access
Research Article10.9734/jpri/2021/v33i331157
Background: Intussusception is an important disease of childhood & has been recognized since ancient time. It commonly involves young infants of 3 ½ months to 10 months of age. Diagnosis is mostly clinical on the basis of classical triad or quarter of pain in abdomen, vomitin...
Open access
Research Article10.9734/jpri/2021/v33i331158