Aim: Guggul lipid, a lipophillic antihyperlipidemic moiety, undergoes extensive first-pass metabolism and has low bioavailability. In order to address this limitation, guggul lipid loaded chitosan nanoparticles (GNPs) were designed, optimized and processed by 3- factor 3- level B...
Open access
Research Article10.9734/jpri/2021/v33i1831316
Loratadine, a second generation H1-receptor antagonist, works by blocking the action of histamine and is widely prescribed for itching, runny nose, watery eyes, and sneezing from "hay fever" and other allergic conditions. To ensure quality the main requirements for a medicinal pr...
Open access
Research Article10.9734/jpri/2021/v33i1731307
Aims: Gastroesophageal reflux disease (GERD) is a common gastrointestinal disorder that develops when the contents of the stomach reflux into the esophagus due to large hiatal hernia or lower esophageal sphincter dysfunction. The common symptoms of the disease include heartburn a...
Open access
Research Article10.9734/jpri/2021/v33i1731308
Pharmacokinetic data of acamprosate tablets was not accessible on large number of human. Rationale to examine the pharmacokinetic properties of acamprosate calcium in healthy male subject, on single or multiple dosage administration, to evaluate the bioequivalence of two formulat...
Open access
Research Article10.9734/jpri/2021/v33i1731310
This paper presents a new analytical method to determine amplitude of density fluctuations of 152 nearby clusters (z ≤ 0.15). We investigate the rms linear fluctuation in the mass distribution on scales of 8h−1M pc i.e. σ8 , by using Press-Shechter mass function. The mass functio...
Coronavirus Disease 2019 (COVID-19) was first reported in December 2019, in the City of Wuhan, China. Within the span of a few weeks, the disease had spread to other regions of China and eventually to different parts of the world. COVID 19 has affected 221 countries and territori...
Open access
Research Article10.9734/jpri/2021/v33i1731309
Aim: For the Method development and validation of Anabasine and Nornicotine in human plasma LC-MS/MS technique is used. Methodology: Operated in positive electron spray ionization which removes the hardness in ions. Metoprolol is used as an internal standard. Mass analyzers are u...
Open access
Research Article10.9734/jpri/2021/v33i1731301
Aims: The effects of exercise/training on biochemical parameters may vary according to the characteristics of individuals, physical conditions, duration and intensity of exercise, and different lipid values. The purpose of this study was to investigate the alterations in muscle d...
Open access
Research Article10.9734/jpri/2021/v33i1731304
Structural equation models are very common in medical, social, management and behavioral sciences where researchers established some causal relations between observed variables and latent variable. In structured populations the assumption of independence of observations is often...
Open access
Research Article10.9734/jpri/2021/v33i1731306
The human body consists of 55-60% water in the case of young adults. There are numerous studies conducted in the 21st c. concerning hydration reaction in sports training and recovery. Dehydration is a natural process during training and competition. Athletes lose both water and m...
Open access
Research Article10.9734/jpri/2021/v33i1631299