Although metformin is currently one of the most frequently prescribed drugs for the treatment of type 2 diabetes, the precise mechanism of its molecular action is not fully understood. Metformin induces mild and transient inhibition of mitochondrial respiratory-chain complex I ac...
Open access
Research Article10.9734/BJMMR/2016/23354
Domingos D. Roque, Karina T. Pomini, Rogerio L. Buchaim, Daniela V. Buchaim, Jesus C. Andreo, Jose S. Roque, Antonio C. Rodrigues, Geraldo M. Rosa Junior, Luis Henrique R. Moraes & Fausto Viterbo·Journal of Advances in Medicine and Medical Research·2015
Aim: The aim of this study was to compare two tubulization techniques, inside-out veins and standard veins, both filled with skeletal muscle or not, in sciatic nerve by morphological and histomorphometric study. Methodology: Seventy Wistar rats were divided in 4 experimental grou...
Open access
Research Article10.9734/BJMMR/2016/23294
This mini-review summarises the risk factors for acquiring Respiratory Syncitial Virus (RSV) infection, and describes the harmful effects of the infection in pre-term infants. Moreover, theoretical considerations are discussed for the prevention of RSV infection in high-risk infa...
Open access
Research Article10.9734/BJMMR/2016/22894
Background: Lactation mastitis is a painful, debilitating condition that if not well managed, can mislead women into prematurely stopping breastfeeding and by so doing deprive the child of optimal feeding. The World Health Organization (WHO) estimates that about 10% of breastfeed...
Open access
Research Article10.9734/BJMMR/2016/23223
Aims: Narrowing of the upper airway during sleep causes snoring, hypoventilation and decreased oxygenation of the brain with recurrent arousal from sleep and a cascade of excessive daytime sleepiness, poor concentration in class and undesirable academic performance. This study de...
Open access
Research Article10.9734/BJMMR/2016/22689
Objectives: The aim of this study was to evaluate the usefulness of different cutoffs applied to the cellularity and various biochemical parameters (BP) (metabolic and enzymatic) to contribute to the etiologic diagnosis of pleural fluids (PF). Design and Methods: We studied 150 s...
Open access
Research Article10.9734/BJMMR/2016/22971
Background: Biobanking today plays a key tool in biomedical research. Establishment and proper running of biobanks in developing countries is confronted with a number of challenges of legal, ethical, and financial nature. Considering that there are no guidelines or regulations to...
Open access
Research Article10.9734/BJMMR/2016/21583
Background: Gingival hyperpigmentation usually occurs due to the abnormal accumulation of melanin in the gingival tissue and confers a dark appearance to the gingiva. Gingival hyperpigmentation often compromises smile esthetics and can occur due to several physiological disorders...
Open access
Research Article10.9734/BJMMR/2016/22428
Sickle cell disease (SCD) is caused by polymerization of abnormal haemoglobin S when oxygen tension decreases. This lead to changes in the shape of red blood cells and anemia. Previous studies have been indicated that some medicinal plants have shown an antisickling activity, whi...
Open access
Research Article10.9734/BJMMR/2016/22795
Carpal coalition is a rare asymptomatic condition and usually detected incidentally. It may be symptomatic after a trauma and causes pain on the medial part of the wrist. Most often, lunotriquetral coalition is seen. The second frequent one is capitate-hamate coalition. It can be...
Open access
Research Article10.9734/BJMMR/2016/19864