Insomnia is when a person feels difficulty falling asleep or staying asleep, often associated with complications, such as fatigue, sleepiness, etc. Insomnia may cause disruptions in daytime physical and mental abilities. Orexins or hypocretins are the neuropeptides secreted from...
Open access
Research Article10.9734/indj/2024/v21i6457
Background: Selective serotonin reuptake inhibitors (SSRIs) are widely prescribed for the treatment of mood disorders, including depression and anxiety. While SSRIs are generally well-tolerated, they can be associated with a range of side effects that can impact patient adherence...
Open access
Research Article10.9734/indj/2024/v21i6456
Kelechi Nelson Adindu, Ogbonnaya Nwagwu AJAH, Komolafe Samuel AYOWALE, Emeka Darlington ONOCHIE, Nkechi Rita ENEMUO & Chukwuka David OKORIE·International Neuropsychiatric Disease Journal·2024
Adolescence is a pivotal developmental stage characterised by significant neurobiological changes that heighten susceptibility to substance abuse. This period is marked by the maturation of the brain regions responsible for decision-making and impulse control, alongside an increa...
Open access
Research Article10.9734/indj/2024/v21i6455
Aims: Neurodegenerative diseases pose a serious threat to public health. Manganese (Mn) is a metal necessary for biological systems; however, it can become hazardous at high concentrations, causing neurological damage. This study explores tamoxifen's potential to protect against...
Open access
Research Article10.9734/indj/2024/v21i6454
Aims: To reveal the geographical distribution of stroke patients in a private university hospital in Jakarta, Indonesia according to their address and further divide them into three sub group of using universal health coverage (UHC) vs other type of insurance ((OTI) vs private no...
Open access
Research Article10.9734/indj/2024/v21i6453
Background: This study evaluated the neuroprotective effects of Bryophyllum pinnatum (B. pinnatum) in ketamine-induced neurotoxicity in Wistar rats, focusing on neurochemical and oxidative stress markers, as well as histological changes in the hippocampus and cerebral cortex. Met...
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Research Article10.9734/indj/2024/v21i6452
Genetics and epigenetics play critical roles in mental health, offering insights into the complex interplay between biological predisposition and environmental influences in the development and progression of mental disorders. Genetic studies have identified numerous risk loci as...
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Research Article10.9734/indj/2024/v21i6451
This study critically evaluates the effectiveness of public health policies and programs targeting Alzheimer's and dementia care in the United States, with a specific emphasis on early detection, disparities in access to care, and variations in service quality between urban and r...
Open access
Research Article10.9734/indj/2024/v21i5450
Neurodegenerative disorders, including Alzheimer's disease (AD), Parkinson's disease (PD), and Huntington's disease (HD), pose significant challenges to global healthcare systems due to their progressive nature and limited therapeutic options. In recent years, natural compounds h...
Open access
Research Article10.9734/indj/2024/v21i5449
Aims: This study aims to investigate the potential therapeutic effects and mechanisms of cannabidiol (CBD) in the treatment of Parkinson's disease (PD). Specifically, it focuses on understanding the role of CBD in managing motor and non-motor symptoms and its neuroprotective prop...
Open access
Research Article10.9734/indj/2024/v21i5448