Oresanya M.E, Ehiremen S.E, Alabi A.O, Adejinmi S.O, Abdusalam M.K, Adelakin L.A, Taiwo-Ola D.O, Banjo T.A, Amballi A.A, Shallie P.D & Fakunle P.B·Asian Journal of Research and Reports in Neurology·2025
5-Fluorouracil (5-FU) is a widely used chemotherapeutic agent known for its neurotoxic side effects, including oxidative stress and behavioral disturbances. This study investigated the neuroprotective potential of Nigella sativa oil (NSO), a natural antioxidant, against 5-FU-indu...
Open access
Research Article10.9734/ajorrin/2025/v8i1136
Background: A cerebrovascular accident (stroke) is a medical emergency that can lead to irreversible brain damage or death. It is a cause of disability and poor quality of life among the paediatric population. This study aims to determine the clinical features and aetiology of st...
Open access
Research Article10.9734/ajorrin/2025/v8i1135
Introduction: Sleep is one of man's primary needs. The quality of sleep improves well-being and consequently the performance of humans in their various activities. The aim of this study was to evaluate the prevalence and determining factors of sleep disorders among health profess...
Open access
Research Article10.9734/ajorrin/2025/v8i1134
Introduction: Oxidative stress and increased reactive oxygen species have been implicated in recurrent seizures, but selenium containing glutathione peroxidase are reported to protect against oxidative damage and promote neuronal cell survival. Aim: We compared levels of seleni...
Open access
Research Article10.9734/ajorrin/2025/v8i1133
Background and Objectives: Cadmium is a potent neurotoxic heavy metal known to induce oxidative stress, apoptosis, and neurotransmitter dysfunction, leading to neurodegenerative effects. Turmeric (Curcuma longa) has gained attention as a natural antioxidant with potential neuropr...
Open access
Research Article10.9734/ajorrin/2025/v8i1132
Wernicke's encephalopathy (WE) is a severe neurological disorder caused by thiamine deficiency, commonly associated with chronic alcoholism. Early recognition and treatment are critical to prevent irreversible neurological damage. We present a case of a 38-year-old male with chro...
Open access
Research Article10.9734/ajorrin/2025/v8i1131
Aims: Psidium Guajava, also called guava is reported to be of high medicinal value due to its phytochemical compositions. The effects of its aqueous leaf extract were investigated in the cerebellum and cerebral cortex of adult Wistar rats. Study Design: Twenty inbred adult male W...
Open access
Research Article10.9734/ajorrin/2025/v8i1130
Background: Burning fossil fuels releases hazardous pollutants, including soot (carbon particulate matter), nitrogen oxides (NOx), and sulfur oxides (SOx). The cerebral cortex, a critical region for cognitive function, is particularly vulnerable to environmental toxins due to its...
Open access
Research Article10.9734/ajorrin/2025/v8i1129
Ezejindu Damian NNABUIHE, Joshua Izuchukwu ABUGU, Enemuo IJEOMA, Doris Kasarachi Ogbuokiri, Agulanna Ambrose ECHEFULACHI, Ezejindu Cosmas Nnadozie, Nneka Alice Sunday-Nweke, Samuel Chukwudi Chime, Augustus Uchenna UGWU, Victoria Onyemachi CHUKWU, Stephanie Ifebuche Abah & Francis Ndubuisi NWODO·Asian Journal of Research and Reports in Neurology·2025
Much attention has been given to the toxic effects of methamphetamine on humans. However, it is not clear whether this toxicity is related to vital organs such as the hippocampus; hence, the present study aimed not only to elucidate the toxic effect of methamphetamine (METH) on t...
Open access
Research Article10.9734/ajorrin/2025/v8i1128
Ehiremen Samuel Ehimare, Yakubu Oluwaseunara Similoluwa, Akanji Omotosho Dhulqarnain, Fakunle Ponle Bamidele, Avwioro Godwin, Olaniyan F. Mathew, Nuhu Sani Usman, Alao Olumide Babatunde & Aina James Oluwatosin·Asian Journal of Research and Reports in Neurology·2025
Introduction: Alzheimer's disease (AD) is a degenerative neural disease that disrupts connections between neurons in the optic chiasm due to an aberrant protein build-up that causes visual field and memory loss. Aluminum chloride accumulation has been linked to cholinergic dysfun...
Open access
Research Article10.9734/ajorrin/2025/v8i1127