Sickle cell disease encompasses diseases that are pathophysiologically caused by hemoglobin S. The HbS component of total hemoglobin in SCD is normally over 50%. HbS is based on an amino acid substitution at position 6 of the β-globin chain, where glutamic acid is replaced by val...
Open access
Research Article10.9734/ajpr/2024/v14i6350
Sandhoff disease is a rare inherited disorder within the sphingolipidosis family, characterized by the accumulation of lipids in the nervous system due to a deficiency in hexosaminidase types A and B enzymes. This condition leads to progressive neurological disorders and eventual...
Open access
Research Article10.9734/ajpr/2024/v14i5348
Allgrove syndrome, or Triple A syndrome, is a very rare autosomal recessive disorder with three key clinical features: achalasia, alacrima, and adrenal insufficiency. Around a third of patients present with additional features, such as neurological and autonomic manifestations (m...
Open access
Research Article10.9734/ajpr/2024/v14i5347
Parents who overschedule their children, put a lot of pressure on them to succeed academically, and want them to act and behave like tiny adults beyond their mental, social, or emotional capabilities are considered to be suffering from the disease known as "hurried child syndrome...
Open access
Research Article10.9734/ajpr/2024/v14i5346
Joaquim Pinto, Yenny Puspitasari, Yuli Periostiwati, Carlos Boavida Tilman, Adelina Pinto & Estevao Menezes Ximenes·Asian Journal of Pediatric Research·2024
Background: Integrated Management of Childhood Illness (IMCI) is needed to address infant mortality in sub-Saharan African and South Asian countries of 11 million cases, due to diarrheal diseases, pneumonia, measles, malnutrition and newborn care problems. (IMCI) is an approach t...
Open access
Research Article10.9734/ajpr/2024/v14i5345
Objective: To investigate the treatment effect of traditional Chinese medicine and massage application in children. Methods: 60 children with Tourette syndrome from three different hospitals were recruited in this study, with 36 males and 24 females. The children were divided int...
Open access
Research Article10.9734/ajpr/2024/v14i5343
Precocious puberty, the premature onset of secondary sexual characteristics before the age of 8 in girls, has emerged as a growing concern in pediatric endocrinology. The prevalence of precocious puberty has witnessed a noticeable rise in recent decades, attributed to various env...
Open access
Research Article10.9734/ajpr/2024/v14i5344
Fatima Bello Jiya, Ango Umar Mohammad, Shu’aibu Jafar Sidi, Muhammad Aminu, Abdullahi Abdulbasit & Hassan Almustapha·Asian Journal of Pediatric Research·2024
Background: Adolescence is a vulnerable stage of life within which there is rapid growth and development and increased nutrients requirement. However, the period of adolescence has been characterized by poor dietary practices that may lead to health problems such as under nutriti...
Open access
Research Article10.9734/ajpr/2024/v14i5342
Primary bile acid disorders (BASD) in newborns are rarely found with a prevalence of 1-9/1,000,000 and include 1-2 % of all cases with neonatal cholestasis. Causes are different gene defects, which lead to liver enzyme defects, which play a major role in both cholic acid pathways...
Open access
Research Article10.9734/ajpr/2024/v14i5340
The incubator for children to improve the survival chances of premature and immature newborns was developed in France as early as 1857. The first device in the United States was built by William Champion Deming at the State Emigrant Hospital on Ward's Island, New York. The first...
Open access
Research Article10.9734/ajpr/2024/v14i4341