Immune checkpoint inhibitors have transformed the management of solid and haematological malignancies by restoring antitumour T-cell activity through blockade of cytotoxic T-lymphocyte-associated protein 4, programmed cell death protein 1, and programmed death-ligand 1. The same...
Open access
Research Article10.9734/aji/2026/v9i1191
Rheumatoid Arthritis (RA) is a chronic autoimmune disorder primarily affecting the joints, leading to pain, swelling, stiffness, and eventual loss of function. Hepatitis B and C are liver infections caused by the hepatitis B virus (HBV) and hepatitis C virus (HCV) that can lead t...
Open access
Research Article10.9734/aji/2026/v9i1190
Background: Incomplete childhood immunization remains a major public health challenge in rural Nigeria, driven by both caregiver- and health system-related factors. This study assessed the determinants of complete childhood immunization using a community volunteer-driven interven...
Open access
Research Article10.9734/aji/2026/v9i1189
Background: In the clinical management of HIV, viral suppression is often the primary focus, yet the underlying immune architecture frequently remains in a state of disharmony. This study investigated the pro-inflammatory (IFN-gamma) and anti-inflammatory (IL-10) profiles of HIV-...
Open access
Research Article10.9734/aji/2026/v9i1188
M. Inchal Kaverappa, Suraj Manjunath Goudar, Bhoomika Prasanna Hiremath, L. A. Ramachandra Prasad, V. G. Shanmuga Priya & Chemmugil·Asian Journal of Immunology·2026
Aims: To develop a multi-epitope vaccine against Cryptococcus neoformans using computational immunoinformatics approaches for the prevention of cryptococcal meningitis. Study Design: Computational in silico vaccine design study. Place and Duration of Study: The study was perform...
Open access
Research Article10.9734/aji/2026/v9i1187
Background: Malaria in pregnancy is associated with adverse maternal and fetal outcomes, partly driven by immune dysregulation and altered cytokine responses. Pro-inflammatory and anti-inflammatory cytokines influence disease severity, yet their precise profiles in malaria-infect...
Open access
Research Article10.9734/aji/2026/v9i1186
R. Nitish Kumar, Parvana Nair, Kesiya Joy, L. A. Ramachandra Prasad & V. G. Shanmuga Priya·Asian Journal of Immunology·2026
Background: Norovirus, a non-enveloped, positive-sense single-stranded RNA virus belonging to the Caliciviridae family, is a leading cause of acute gastroenteritis (AGE) globally, accounting for approximately 19–21 million cases annually in the United States alone. The rapid emer...
Open access
Research Article10.9734/aji/2026/v9i1184
Shelly Chinwe Ogbu, Moses Zira Zaruwa, Mairiga Jamey Peters, Arikpo Kebe Etim, Chi-kadibia Theophilus Ukoma, Benson Obiageli, Ernest Ikechukwu Ogbu & Christiana Bala Joseph·Asian Journal of Immunology·2026
Pharmacological exploitation of natural compounds has lead to the development of non-synthetic and non-toxic agents that are promising at ameliorating the menace of neoplastic diseases such as leukemia. The aim of this study was to determine the phytochemical and anti-leukemic ef...
Open access
Research Article10.9734/aji/2026/v9i1185
Staphylococcus aureus is a prevalent pathogen in both hospital and community settings and is frequently implicated in wound infections. In light of its clinical significance, the research was carried out to determine the prevalence of mec-A positive Staphylococcus aureus and PVL...
Open access
Research Article10.9734/aji/2026/v9i1183
Background: In early childhood, type 1 diabetes mellitus (T1DM) is an autoimmune illness marked by the death of pancreatic β-cells by the immune system. Autoantibodies that are important indicators of illness etiology and diagnosis include insulin autoantibodies (IAA), glutamic a...
Open access
Research Article10.9734/aji/2026/v9i1182