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All published articles 117777

Studying the Possible Biotransformation of the Cytotoxic Diterpenoid Paclitaxel Using Jatropha Curcas Cell Suspension Culture

Sara A. Nassar, Sherweit H. El-Ahmady, Abla H. Nassar & Mohamed M. Al-Azizi · European Journal of Medicinal Plants · 2013

Aims: To establish a cell suspension culture of Jatropha curcas, family Euphorbiaceae for the biotransformation of the diterpenoid anti-cancer compound paclitaxel. Study Design: The development and maintenance of callus lines from the leaves and petioles of J. curcas and the stud...

Open access Research Article 10.9734/EJMP/2013/2881

Stability Indicating Methods for Determination of Nalbuphine- Hydrochloride

M. M. Fouad, S. A. Abdel Razeq, Z. A. Elsayed & L. A. Hussin · Journal of Pharmaceutical Research International · 2013

Three simple, sensitive and reproducible spectrometric methods for the selective determination of nalbuphine–HCl in presence of its oxidative degradate were investigated. The first method depended on the quantitative densitometric evaluation of thin layer chromatograms of the dru...

Open access Research Article 10.9734/BJPR/2013/2443

Ethanopharmacological and Phytochemical Aspects of Ocimum sanctum Linn- The Elixir of Life

Baby Joseph & Vrundha M. Nair · Journal of Pharmaceutical Research International · 2013

Ocimum sanctum Linn. (Tulsi), a sacred and traditional medicinal plant of India which belongs to the family Lamiaceae possesses innumerable health benefits and therefore regarded as the “Elixir of Life”. The entire plant body including its leaves, stem, root, inflorescence and se...

Open access Research Article 10.9734/BJPR/2013/2433

Theoretical Study of Stability, Tautomerism, Equilibrium Constants (pKT) of 2-Thiouracil in Gas Phase and Different Solvents (Water and Acetonitrile) by the Density Functional Theory Method

N. Surendra Babu · Chemical Science International Journal · 2013

A density functional theory (DFT) calculations were carried out to investigate the relative energies, equilibrium constants and dipole moments of 2-thiouracil in the gas phase and in solutions with different polarities. Solvent effects were examined by means of the self-consisten...

Open access Research Article 10.9734/ACSJ/2013/2905

Farnesol Sensitivity of Serum Induced Yeast to Hyphae Morphogenesis: A Study on Fifty Clinical Isolates of Candida albicans

Vimal S. Rathod, Jayant S. Raut, Sharmila S. Raut, Sanjay R. More & Sankunny Mohan Karuppayil · Microbiology Research Journal International · 2013

Aim: Objective of this study was to examine farnesol sensitivity of yeast to hyphae dimorphism in clinical isolates of Candida albicans. Study Design: Variations in virulence attributes contribute to variations in pathogenicity of C. albicans. Ability to switch from yeast to hyph...

Open access Research Article 10.9734/BMRJ/2013/2939

Persistent Bactericidal Action by a Silver Disinfectant on Surfaces of Hospital Furniture

Sonia De Lorenzi, Italo Barrai, Gianfranco Finzi, Paola Cugini & Germano Salvatorelli · Microbiology Research Journal International · 2013

Aims: In hospitals, surfaces are often colonized by potentially pathogenic micro organisms which can remain alive for long periods of time, thus playing a major role in hospital-acquired infections. One way to overcome this drawback could be to use disinfectants with long-term ac...

Open access Research Article 10.9734/BMRJ/2013/2761

Formulation and In vitro Evaluation of Fluconazole Topical Gels

Aml Mekkawy, M. Fathy & Sohair El-Shanawany · Journal of Pharmaceutical Research International · 2013

Aims: Topical drug delivery of fluconazole, an antifungal drug, in gel form was formulated to avoid the side effect of the oral route. Study Design: In this study I prepare different formulation from different polymers and select the best formulation to undergo further antifungal...

Open access Research Article 10.9734/BJPR/2013/2775

A Study to Evaluate the Symptomatic Efficacy and Safety of LafaxidTM (Lafutidine 10mg) in Patients with Acid Peptic Disorders in India

Bhupesh Dewan & Deepashri Shah · Journal of Advances in Medicine and Medical Research · 2013

Aims: To evaluate the symptomatic efficacy and safety of Lafaxid™ (lafutidine 10 mg) in Indian patients with Acid Peptic disorder (APD). Study Design: An observational, prospective, uncontrolled, open-label multi-centric study. Place and Duration of Study: Patients were recruited...

Open access Research Article 10.9734/BJMMR/2013/2328

Purpose in Life/Ikigai and Moderate Exercise may Prevent and Improve Violent Behavior: with Consideration of the Traits of Neurotransmitters and Hormones

Riichiro Ishida · Journal of Advances in Medicine and Medical Research · 2013

The prefrontal lobe, which is more evolved in humans compared to other mammals, has extensive connections with many other areas of the brain including the thalamus, hypothalamus, hippocampus, and amygdala. The prefrontal lobe functions include ambition, cognition, emotions, infor...

Open access Research Article 10.9734/BJMMR/2013/2410

Early-onset CMT1B due to the MPZ mutation c.320A>T associated with collateral inclusion body myopathy and Deafness

Josef Finsterer, Christine Haberler & Michaela Auer-Grumbach · Journal of Advances in Medicine and Medical Research · 2013

Aims: To present the case of a patient with early-onset demyelinating neuropathy due to a MPZ-mutation, associated with deafness and inclusion-body-myopathy. Methods: Nerve conduction studies, electromyography, muscle biopsy, genetic testing. Results and Discussion: In a 46yo mal...

Open access Research Article 10.9734/BJMMR/2013/2944

CT Findings of Pulmonary Involvement in Antiphospholipid Syndrome

Argyris Tzouvelekis, Panagiotis Skendros, Panagiotis Prassopoulos, Ioannis Mitroulis, Eirini Apostolidou, Adina Thomaidi, Konstantinos Ritis, Demosthenes Bouros & Anastasia Oikonomou · Journal of Advances in Medicine and Medical Research · 2013

Aims: Antiphospholipid syndrome (APS) is a systemic autoimmune disorder characterized by vascular thrombosis. Pulmonary changes regarding interstitium and airways have not been described in APS. Our aim was to determine the prevalence of nonthrombotic pulmonary CT manifestations...

Open access Research Article 10.9734/BJMMR/2013/3007