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All published articles 7450

Assessing the Clinical Improvement in Patients with COVID-19 using Lopinavir-Ritonavir: A Systematic Review

Rania M. Magadmi · Journal of Pharmaceutical Research International · 2021

Aims: Globally the focus is towards finding an effective treatment for COVID-19 patients in order to suppress the spread of this pandemic disease. An antiviral combination of lopinavir-ritonavir is considered to be effective in treating COVID-19 patients. Therefore, the present s...

Open access Research Article 10.9734/jpri/2021/v33i44A32637

Febrile Convulsions in Anemic Children: A Review

Hassan Tag Elkhatim Mohamed, Ibtisam Khulaif Alruwaili, Maisa Hamad Freaj Alenazi, Ahlam sultan alanazi & Norah Thyap Matar Alenezi · Journal of Pharmaceutical Research International · 2021

Febrile convulsions are the most common type of convulsions that affect children aged 6 months to 5 years old. Iron deficiency anemia could be a risk factor for febrile convulsions as was suggested by some studies, for the reason that febrile convulsions is common in children und...

Open access Research Article 10.9734/jpri/2021/v33i44A32630

Nephrectomy in Patient of Chronic Pyelonephritis with Non Functioning Kidney on Left Side: A Case Report

Swapna G. Morey, Ranjana Sharma & Deepali Ghungrud · Journal of Pharmaceutical Research International · 2021

Introduction: There are two types of renal surgery i.e. partial nephrectomy and one other is total nephrectomy. Mostly, nephrostomy performs in malignant tumors of the renal. Sometimes it performs in kidney injury due to that no longer function and it may create any obstructive d...

Open access Research Article 10.9734/jpri/2021/v33i44A32631

An updated Review on Therapeutic Potential of Entrectinib as a Promising TrK, ROS 1, and ALK Inhibitor in Solid Tumors and Lung Cancer

M. Archana, Mariya Palathingal, K. Athulya Damodharan, P. Ashisha & Nuaman, Akash Marathakam · Journal of Pharmaceutical Research International · 2021

Entrectinib is a selective inhibitor of tyrosine kinases , tropomyosin receptor kinases that targets oncogenic rearrangements in Neurotropic Tyrosine Receptor kinase, c-ros oncogene 1 and Anaplastic lymphoma kinase used for the treatment of various solid tumors. Entrectinib gaine...

Open access Research Article 10.9734/jpri/2021/v33i44A32633

Etiology, Pathogenesis, Diagnosis, and Treatment of Fibromyalgia Syndrome

Mohammed Salah Hussein, Majed Talal Al nujaiman, H. Althomali, Abdullah Mohammed, Marwan Naif Alsehli, Laila Mohammed Mujarribi, Mohammed Wasel A. Mukhtar, Abdullah Saad A. Alsharif, Safwan Mohammed M. Alim & Bandar Hamdan Jasi Alshamrani · Journal of Pharmaceutical Research International · 2021

Fibromyalgia is a common syndrome (FM) that is prevalent all over the world with different prevalence rates in each country. The etiology and pathogenesis of fibromyalgia are still unknown, unclear, and with uncertain pathophysiology. Diagnosis of fibromyalgia is not that easy be...

Open access Research Article 10.9734/jpri/2021/v33i44A32641

Occurence of Genotypes of Hepatitis C Virus in Hepatitis C Patients at Civil Hospital Khairpur, Sindh, Pakistan

Sajid Ali, Ikram Ahmed Tunio, Rukia Farzana, Muhammad Siddique Rajput, Qararo Shah, Saima Samtio, Saleem Ahmed Joyo & Arslan Ahmer · Journal of Pharmaceutical Research International · 2021

Objective: To evaluate frequency of Hepatitis C virus Genotypes in Hepatitis C patients reported at Civil Hospital Khairpur, Sindh, Pakistan. Methodology: A descriptive cross sectional study was conducted on 223 hepatitis C patients who fulfilled the criteria at hepatitis OPD of...

Open access Research Article 10.9734/jpri/2021/v33i44A32627

Evaluation on Safety and Efficacy of Selective Anti-Hypertensive Drugs in Patients with Cardiovascular Disease at a Tertiary Care Hospital, India-an Observational Study

R. E. Ugandar, Umadevi Iluru, Mariamma Bethe, C. Bhargava Reddy & Kiran C. Nilugal · Journal of Pharmaceutical Research International · 2021

Background: Hypertension means persistent elevation of Blood Pressure in arteries. It is the second leading cause of death. The symptoms include Severe Headache, Drowsiness, Vision problem, Nose bleed, fatigue, Confusion. It may lead to various types of Cardiovascular disorders s...

Open access Research Article 10.9734/jpri/2021/v33i44A32629

The Relationship between Visual Discomfort and Academic Performance among Medical Students at King Abdulaziz University, Jeddah, Saudi Arabia

Anan A. Aljawi, Albandri A. Alahmari, Amaal M. Alharbi, Aseel T. Baflah, Fatimah A. Alhaddad & Nizar M. Alhibshi · Journal of Pharmaceutical Research International · 2021

Background: Visual discomfort or asthenopia is presented through unpleasant somatic and perceptual symptoms including headaches, fatigue, light sensitivity, blurred text, diplopia, movement of letters, and fading and impaired reading performance. Its etiology can be prolonged exp...

Open access Research Article 10.9734/jpri/2021/v33i44A32632

Method Development for the Control of Potential Genotoxic Impurities in Vigabatrin Using Gas Chromatography Techniques and Mass Spectroscopy Detector

D. Srikanth, S. Ganapaty, P. Manik Reddy, K. Sunitha & G. Sowjanya · Journal of Pharmaceutical Research International · 2021

Aim: To develop a sensitive headspace GC-MS method for the determination of potential genotoxic impurities in Vigabatrin. Place and Duration of Study: The study was performed in SIONC Pharmaceuticals, Visakhapatnam from June 2020 to March 2021. Methodology: The impurities were de...

Open access Research Article 10.9734/jpri/2021/v33i44A32634

Factors Influencing the Consumption of Fast Food among Young Adults

S. Rajini, K. Kannan & Tamil Selvi · Journal of Pharmaceutical Research International · 2021

Background: The habit of consuming the fast- foods and packed foods are increased among the people in developing countries. Besides, several studies showed that the fast- food eating brings higher risks for developing the physiological imbalances such as obesity, over – weight ev...

Open access Research Article 10.9734/jpri/2021/v33i44A32635

Role of Breast-Feeding in Postnatal Women

Sowmiya Sri, Nithya · Journal of Pharmaceutical Research International · 2021

To assess the attitude of breastfeeding in postnatal women. Breastfeeding is essential for the health and development of the child. It is protective against gastrointestinal and respiratory infections of the baby. Early initiation of breastfeeding, exclusive breastfeeding and int...

Open access Research Article 10.9734/jpri/2021/v33i44A32636

Relationship of Amniotic Fluid Index (AFI) Between Maternal and Perinatal in Patients

Manimekalai, Neranjana · Journal of Pharmaceutical Research International · 2021

Background: Alcohol amniotic, a protecting fluid that surround the embryo. It protects from concussion, pressure, desiccation, reminiscent of the aquatic origin of life. Adequate amount of amniotic fluid is essential requirement for the normal development and it acts like a cushi...

Open access Research Article 10.9734/jpri/2021/v33i44A32638

Antibody Response of Buffalo Calves to Different Levels of Foot and Mouth Disease Virus Immunogen

Qaiser Akram, Shahid Hussain Farooqi, Hafiz Muhammad Rizwan, Beenish Zahid, Muhammad Ahsan Naeem, Qurban Ali, Asif Idrees, Muhammad Sulman Ali Taseer, Muhammad Umar Farid & Zeeshan Iqbal · Journal of Pharmaceutical Research International · 2021

Antibody response of buffalo calves to different levels of Foot and Mouth Disease (FMD) virus immunogen was investigated. Vaccine containing 106.2 units of immunogen/TCID50 of FMD virus (O, A and Asia-1) serotypes induced log2 (1.3± 0.4) units of anti-FMD O Complement Fixing Geom...

Open access Research Article 10.9734/jpri/2021/v33i44A32639

Design, Synthesis, Molecular Docking and Biological Evaluation of Novel 2-[(2-{[5-(Pyridin-4-yl)-1, 3, 4-Oxadiazol-2-yl]Sulfanyl}Ethyl)Sulfanyl]-1,3-Benzoxazole

Anees Fathima, H. M. Vagdevi, N. D. Jayanna, R. Mohammed Shafeeulla & . Subbaraju · Journal of Pharmaceutical Research International · 2021

In the present communication, a simple and facile method was adopted to synthesize  a series of novel 2-[(2-{[5-(pyridin-4-yl)-1,3,4-oxadiazol-2-yl]sulfanyl}ethyl)sulfanyl]-1,3-benzoxazole by fusing 5-(pyridin-4-yl)-1,3,4-oxadiazole-2-thiol with substituted 2-[(2-bromoethyl)sulfa...

Open access Research Article 10.9734/jpri/2021/v33i44A32640

Goat’s Milk as a Potential Anti-proliferative against Colon Cancer Cell Lines

Nurhashimah Dahlan, Jamila Khayrin Baharum, Norhaslinda Ridzwan, Mimie Noratiqah Jumli, Norhayati Abd Hadi, Roslan Arshad, Atif Amin Baig, Mohd Adzim Khalili Rohin, Che Abdullah Abu Bakar & Ahmad Zubaidi A. Latif · Journal of Pharmaceutical Research International · 2021

Aim: To investigate anti-proliferative effect of fresh and pasteurized goat milk against colon cancer cell lines (HT-29, HCT-116, CT-26). Study Design: Experimental study. Place and Duration of Study: Central Laboratory, Tissue Culture Laboratory, Universiti Sultan Zainal Abidin,...

Open access Research Article 10.9734/jpri/2021/v33i44A32642