Heart disease due to valvular anomaly has increased prevalence along with increasing age. Rheumatic heart disease is a condition in which the heart valves have been permanently damaged post rheumatic fever. The operative management including reparation or substitution with prosth...
Open access
Research Article10.9734/jpri/2021/v33i46A32879
Pharmacovigilance is a tool proposed during the post-marketing process of the pharmaceutical product lifecycle to monitor drug safety in everyday life and to identify adverse drug reactions. The identification of adverse reactions, however, is a significant cause of concern and a...
Open access
Research Article10.9734/jpri/2021/v33i46A32867
Aims: The current work was analyzed in antioxidants, cytotoxicity and larvicidal potential were examined for O. latifolia methanolic leaf extract. Methodology: Antioxidant assasy for Hydroxyl radical (H2O2). Cytotoxicity potential was studied against colon (HT-29). Culex quinquef...
Open access
Research Article10.9734/jpri/2021/v33i46A32866
Introduction: Experimental studies are essential and expected part of a new drug development. The studies are conducted to know about the toxic effects (if any), produced by the drug & to access safety of the drug. Studies also help to ascertain the efficacy of the drug &...
Open access
Research Article10.9734/jpri/2021/v33i46A32868
Background: Nocturnal enuresis, also called bedwetting, is involuntary urination while asleep after the age at which bladder control usually begins. Bedwetting in children and adults can result in emotional stress. Little is known about toilet training in pre-modern societies, bu...
Open access
Research Article10.9734/jpri/2021/v33i46A32869
Oral benign tumors are common in the Indian subcontinent. These benign neoplastic lesions may mimic other tumors like lesions or malignant tumors of the oral cavity. Aim: The current study's goal is to investigate the demographical distribution of benign tumors of the oral cavity...
Open access
Research Article10.9734/jpri/2021/v33i46A32870
The current study was planned to assess the different oxidative, Endocrinological and biochemical parameters using extract of Catharanthus roseus (C. roseus) on diabetic rats. Three groups of Diabetic rats were assigned viz. Group A have Negative Control which was fed basal diet;...
Open access
Research Article10.9734/jpri/2021/v33i46A32871
Purpose: A HPLC method for Fingolimod was developed using a Quality by Design concept. QbD has gained importance in recent times due to regulatory requirements. Actual study was started after determination of target profile and qualification of instrument. Methods: Separation was...
Open access
Research Article10.9734/jpri/2021/v33i46A32872
Pioglitazone HCl is an oral anti-diabetic agent used for the treatment of diabetes mellitus type II. The aim of the present work is to evaluate the pharmacodynamic activity of solid lipid nanoparticles of pioglitazone HCL prepared by using solvent injection technique and to compa...
Open access
Research Article10.9734/jpri/2021/v33i46A32873
Purpose of Review: Chronic rhinosinusitis (CRS) is denoted as the symptomatic inflammations of sin nasal mucosa persists for ≥12 weeks. The purpose of this study was to review the recent literatures for digging out a clear concept on the clinical presentations of patients with ch...
Open access
Research Article10.9734/jpri/2021/v33i46A32864
In present time the technological & computing evolution are promoted for new opportunities that will help to improve the standard of life between the new medical accomplishments, in particular and the standard of diagnostic evaluations. MRI is one of the imaging equipment for...
Open access
Research Article10.9734/jpri/2021/v33i46A32855
A simple, rapid, selective, and reproducible Gas chromatographic mass spectrometry (GC-MS) method has been developed and validated for the estimation of Diethyl Phosphite content in Foscarnet Sodium USP Drug substance. The drugs were estimated using HP-5, Length-30 M, Internal di...
Open access
Research Article10.9734/jpri/2021/v33i46A32857
In the present time the Mortality rate will be increased all around the world on their daily basis. So the cause for this might possibly be largely ascribe to the developing in the numbers of the patients with the cardiovascular patient’s diseases. To aggravate the cases, many ph...
Open access
Research Article10.9734/jpri/2021/v33i46A32858
Sclerotium stipitatum Berk. et. Curr., locally known as ‘nilamanga’ is a rare macro fungus, traditionally used to treat numerous diseases like arthritis, earache, jaundice etc. The present study aims to evaluate the anti-inflammatory activity of ethanol extract of S. stipitatum a...
Open access
Research Article10.9734/jpri/2021/v33i46A32859
Heat Stroke is a kind of medical emergency that can cause severe dehydration and neurological changes as a result multi-organ injuries or failure could be possible. Heat strokes occur when the body temperature exceeds 40 0C due to external heat and humidity. The liver is widely a...
Open access
Research Article10.9734/jpri/2021/v33i46A32860