Aims: New validated method for the estimation of Mobocertinib using HPLC and study of its degradation. Place and Duration of Study: Department of Chemistry, RVR & JC College of Engineering, Chowdavaram, Guntur, Andhra Pradesh, between February 2021 and August 2021. Methodolog...
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Research Article10.9734/jpri/2021/v33i46B32927
Arub Adnan Yousef, Sultanah Rawi Abdullah Alanazi, Fatimah Mofareh Murid Alanazi, Sarah fereih meraid alenezi, Ahmed Mahmoud R Abdullah & Mohammed Ghannam Thallab Alharbi·Journal of Pharmaceutical Research International·2021
Background: Several studies have found a link between stress and thyroid disorder, the majority of evidence supporting stress contributing to the start and progression of autoimmune illness is circumstantial, and the mechanisms by which stress impacts thyroid is not fully underst...
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Research Article10.9734/jpri/2021/v33i46A32901
Ashwag Siddik Noorsaeed, Asiri, Alaa Mohammad A., Abdulmalk Abdulatif A. Almaghrabi, Alshawi, Eyad Ibrahim N., Rinad Ameer Nawab, Fahad Khaled M. Alkahtani, Abdullah Saad Alqarni, Reema Abdulaziz D. Alsaadi, Deemah Muneer Alhamawi, Ayman Hasan Kaabi, Khalid Ahmed H. Aljehani, Sana Zaki Alburaiki & Osama Saeed Aljuraysh·Journal of Pharmaceutical Research International·2021
Implant placement necessitates an interdisciplinary approach in which a team of dental implant specialists, including an oral surgeon, prosthodontist, periodontist, and oral radiologist, collaborate on the design, execution, and maintenance of the implants to provide the best pos...
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Research Article10.9734/jpri/2021/v33i46A32903
Mazen Bishrah, Abdullah Mohammedamin M. Tashkandi, Abdulelah Khalid A. Bahabri, Hessa Khalid Almuhaisen, Mawadah Ismaeel Nooh, Fatimah Hussain Ali Dallak, Joud Awad Alhamdi, Rahaf Ahmed Alrashidi, Ahmad Abdulrahman Rahbeeni, Amjad Ali Albannay, Albatool Wali Gotah, Yousuf Loai F. Ramadan, Sara Abdulmohsen Almulhim & Alanoud Abdulaziz Alharkan·Journal of Pharmaceutical Research International·2021
Hysterectomy is one of the most prevalent surgical procedures in the United States. Vaginal hysterectomies have been successfully performed for nearly two centuries. Abdominal hysterectomy remains the most prevalent surgical strategy, with laparotomies accounting for well over ha...
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Research Article10.9734/jpri/2021/v33i46A32905
Mohammed Salah Hussein, Ziyad Abdullah Alshagawi, Noor Abdulhakim M. Al Fateel, Hossam Mohammed Alashhab, Alenzi Meshari Mosleh, Osamah Abdulmonem Almutawa, Abdulrahman Oun Alshahrani, Mohammed Faisal G. Alahmadi, Saleh Kamal Alzahrani, Wed Mohammed Khorami, Naif Mohammed Al-Wagdani, Abdalrhman Nbil Bokhari, Wafa Faisal W. Aljadrawi & Abdulrahman Ghorom Malhan·Journal of Pharmaceutical Research International·2021
Gastrointestinal (GI) bleeding from the colon is a communal reason for hospitalization and is being more frequent in older patients. Gastrointestinal bleeding is known as any bleeding that takes place in the GIT from mouth to anus. Lower GI bleeding is defined as bleeding distal...
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Research Article10.9734/jpri/2021/v33i46A32907
Introduction: HIV/AIDS is becoming a growing global danger to mankind. Since the first cases were reported, HIV/AIDS has been spreading at an alarming rate. Background: In India, The age group of 15-24 years accounts for 35% of all AIDS cases, indicating that the younger populati...
Open access
Research Article10.9734/jpri/2021/v33i46A32902
Background: Fms-like Tyrosine Kinase 3 (FLT3) has an important role to perform in hematopoietic malignancy pathogenesis. Hence the focus of several studies has recently been FLT3. Objective: To determine the molecular characterization of FLT3 mutation in patients of acute leukemi...
Open access
Research Article10.9734/jpri/2021/v33i46A32904
Breast cancer is one of the predominant cancers in Indian subcontinent and the global scenario is not very different. Treatment of this type of cancer is possible by chemotherapy, surgery, and radiotherapy, which relieve the patient; however, off target activity and severe toxici...
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Research Article10.9734/jpri/2021/v33i46A32906
Hisham Mohammed Sonbul, Abdulrahman Mohammed S. Alabid, Fahad Ali A. Almarshad, Alqahtani, Ali Saad M., Rayan Ali Barakat, Abudeyah, Manal Ahmed K., Ameera Jassim A. Al Ramadhan, Muteb Bandar Binmohaiya, Alqarni, Alwaled Abdullah B., Hayash, Fatimah Abdulrahman H. & Abdulelah Ahmed Alabdulwahab·Journal of Pharmaceutical Research International·2021
Disseminated intravascular coagulation (DIC) is life threatening disease it’s often associated with sepsis, which require ICU management. In individuals with sepsis, the risk of DIC is especially high, DIC affects 30 to 50 percent of these individuals. Also it affects only about...
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Research Article10.9734/jpri/2021/v33i46B32908
In-silico analysis is being used nowadays as an efficient method for drug design to address the pharmacokinetic profile of the drug under study and also to predict the optimized orientation of the ligand against a specific drug target by docking software. It is a cost-effective a...
Open access
Research Article10.9734/jpri/2021/v33i46B32909
Background: Recurrent aphthous stomatitis (RAS) is a chronic ulcerative disease with a complex aetiology and a strong immunological basis. The prototypical pro-inflammatory cytokine is interleukin-1 (IL-1). IL-1alpha and IL-1beta are the two subtypes of IL-1. The proinflammatory...
Open access
Research Article10.9734/jpri/2021/v33i46B32913
Faisal Suliman Algaows, Hasan Taha Obaid, Saleh Mohammed AL Sharyah, Dhafer Ahmed Alshehri, Yazeed Hadi Alharbi, Haitham Ahmed Althawab, Abdulrahman Mustafa Adnan, Abdalrhman Nbil Bokhari, Mohammed Abduljalil Alkhamis, Abdulaziz Ahmed Alansari, Talal Saad Alharbi, Nadia Mubarak Alghamdi & Saeed Oudah Alasiri·Journal of Pharmaceutical Research International·2021
The glucose tolerance test can be performed in a variety of situations. To evaluate a person's capacity to manage a glucose load, a glucose tolerance test is utilised. The test can determine whether or not a person can metabolise a specific amount of glucose. and oral glucose tol...
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Research Article10.9734/jpri/2021/v33i46B32910
Introduction: Spinal instrumentation in idiopathic adolescent scoliosis (AIS) aims to correct spinal deformity, and maintain spinal stability. Proximal junctional kyphosis (PJK) is a relatively common postoperative complication. Posterior-only fusion using diverse instruments suc...
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Research Article10.9734/jpri/2021/v33i46B32911
Hayat AL Zahiry, Futoon Jomman Ali Alomari, Abdullah Mohammed Alharbi, Mohannad Mohammad Almanea, Nehal Fahad Almasri, Mohammed Ahmed Sanguf, Ahmed Hakeem Al-Qarross, Ahmed Abdulaziz Alanazi, Ali Sami Alanazi, Elham Ahmed H. Hakami & Mohammed Sulaiman Alkathery·Journal of Pharmaceutical Research International·2021
Dynamic and static reconstruction procedures are employed for facial reanimation in patients suffering from facial nerve paralysis. Denervation and paralysis of the facial nerves causes considerable psychological and functional damage. Facial paralysis can affect facial expressiv...
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Research Article10.9734/jpri/2021/v33i46B32912
Abdullah I. Aedh, Ali Dhafer Al-Swedan, Abdulaziz S. Alshahrani, Eisa Yazeed Ghazwani, Salem Ali S. Alatef Sultan, Naif Ahmed Y. Mahnashi, Ali Hadi M. Alyami, Ahood Ahmad A. Mahjari, Asaad M. A. Babker & Hatem Mohamed·Journal of Pharmaceutical Research International·2021
The unprecedented pandemic has been causing devastating damage to the human life and livelihood. The SARS CoV-2 viral strains are currently responsible for the serious of infection waves and high mortality rate. The management of disease requires well developed medical infrastruc...
Open access
Research Article10.9734/jpri/2021/v33i46B32914