The word neurodegeneration refers to defects in neuronal structure and consequently its function. The main characteristics of these disorders are relentless progression and cognitive declination. Epilepsy is one of the neurodegenerative disorders, around 50 million people in the...
Open access
Research Article10.9734/jpri/2021/v33i51B33519
Aims: This studies aims at the synthesis of new heterocyclic systems and study its biological and pharmacological properties. Objective: This study was designed to synthesized some quinoxaline-2,3-dione with sulfonamide moiety, characterize the synthesized compounds, and study th...
Open access
Research Article10.9734/jpri/2021/v33i51B33521
Background and Aim: Mesenteric lymphadenitis in pediatric population usually presents with abdominal pain mimicking appendicitis mounting a challenging task for physicians to diagnose. It is a self-limiting inflammatory process and resolves spontaneously. In addition to clinical...
Open access
Research Article10.9734/jpri/2021/v33i51B33522
The article confers a scalable manufacturing process of Fenspiride HCl. 4-aminomethyl-1-(2-phenylethyl)-piperidin-4-ol is the main building block in Fenspiride HCl synthesis. The reported reagents for 4-aminomethyl-1-(2-phenylethyl)-piperidin-4-ol synthesis are costly, explosive,...
Open access
Research Article10.9734/jpri/2021/v33i51B33523
Objective: To determine the instrument preference among obstetricians practicing operative vaginal deliveries and to determine the prevalence and risks of vacuum or forceps Assisted Vaginal Delivery (AVD). Methods: This cross-sectional study was carried out in ACS Medical and Hos...
Open access
Research Article10.9734/jpri/2021/v33i51B33524
Aims: The aim of current study is to evaluate adhesive force and qualitative mycological culture analysis of Denture adhesive (DA) after incorporating antifungal agent in various concentrations. Study Design: Experimental study. Place and Duration of Study: The current study was...
Open access
Research Article10.9734/jpri/2021/v33i51B33525
Objective: To measure the influence of Nigella sativa on testosterone level of albino rats treated with doxorubicin Study Design: Investigational study. Place of Study: Animal House, JPMC, Karachi, Materials and Methods: This study was accompanied on 3-4 months old, 40 albino rat...
Open access
Research Article10.9734/jpri/2021/v33i51B33526
Leiomyomas are benign tumors of the uterus affecting women of the reproductive age group. They are the most common gynaecologic neoplasms in women. The aim of our study was to analyse and correlate the histopathological findings of leiomyomas in 203 hysterectomy specimens receive...
Open access
Research Article10.9734/jpri/2021/v33i51B33527
Yellow fever is a neglected hemorrhagic disease with a high case fatality rate ranging between 25% and 50% for the hospitalized patients. Yellow fever disease is caused by a zoonotic pathogen known as yellow fever virus. This RNA virus is usually transmitted by mosquitos and it i...
Open access
Research Article10.9734/jpri/2021/v33i51B33528
Complications are a reality in healing fractures. Most can be stopped or reduced by being aware of their pathophysiology. Others, though, are inevitable, but their Early diagnosis and effective treatment can help recovery. Significant complications Are Osteomyelitis, delayed unio...
Open access
Research Article10.9734/jpri/2021/v33i51A33499
Aging have an impact on the pharmacokinetic and pharmacodynamic characteristics of drugs, resulting in clinically relevant safety and efficacy consequences. There appear to be a rise in gastrointestinal (GI) problems with age, and certain slight variations in the GI tract have be...
Open access
Research Article10.9734/jpri/2021/v33i51A33500
Fahimeh Shahjooie, Sadrollah Mahmudi, Somayeh Mohammadi, Hassan Goodarzi, Mehrdad Farajy, Mohammadreza Ghanee, Akbar Ghorbani Alvanegh & Amirhossein Ghazale·Journal of Pharmaceutical Research International·2021
Introduction: Wide spectrum of clinical features of COVID-19 was seen from mild to severe. This is very important to determine the severity of disease, early management of severe disorder may increase the chance of survival. Methods: This cross sectional study perform on 150 pati...
Open access
Research Article10.9734/jpri/2021/v33i51A33474
Background: Piper longum, a traditional plant used for regenerative medicine commonly known as the long pepper, is used to treat many pathological conditions. Piper longum is used as a source for obtaining the production of various nanoparticles and testing their efficacy. Piper...
Open access
Research Article10.9734/jpri/2021/v33i51A33501
Muazzam Sheriff Maqbul, Muaadh Badr Saeed, Solafa Azzouz, Amal Bahafi, Tasneem Mohammed, Aejaz A. Khan, S. M. Shakeel Iqubal, Kayamkani Abedulla Khan, Ibrahim Ahmed Shaikh, Uday M. Muddapur & Moustafa Elsayed Abdelaziz Elsayed Elsaa·Journal of Pharmaceutical Research International·2021
This study was aimed to seek out the awareness and knowledge about the covid-19 during the onset of the pandemic among the urban population of the Saudi arabia. This study was carried out for a period of three months from 01.04.2020 to 31.07.2020 and a sample of 1000 participants...
Open access
Research Article10.9734/jpri/2021/v33i51A33502
Hyder Osman Mirghani, Rayyan Fahad H. Altemani, Yousef Hussain J. Alharthi, Mohammed Abdulhafith R. Alotaibi, Ahmed Marwan A. Alamrani, Abdulaziz A. Altawili, AlTurki Abdulrahman Mohammed, Maram Yehia M. Alzahrani, Manar Abubaker A. Bawadood, Asawir Mohammed Al Qurashi, Mohammed Aboubaker R. Alshafey, Amal Mohammad H. Albalawi, Nahaa Eid B. Alsubaie, Aisha Abdullah Alamari & Saud Abdulrahman Saad Alghamdi·Journal of Pharmaceutical Research International·2021
Background: Headaches disorders have a significant burden on the world. Tension Type Headache is the most common type among primary headaches. Since medical students are exposed to a lot of stress, and it is associated with a tension-type headache, the importance of this study co...
Open access
Research Article10.9734/jpri/2021/v33i51B33504