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Comparative Evaluation of Open Flap Debridement Therapy with Two Different Types of Platelet Concentrates, T-PRF and L-PRF as Adjuncts- A Systematic Review

Gowri Pendyala, Ekta Srivastava, Babita Pawar, Satish Manthena, Swati Pustake, Saurabh Joshi, Ameet Mani & Vidyasagar Mopagar · Journal of Pharmaceutical Research International · 2021

Conventional Periodontal therapy such as scaling and root planing and open flap debridement aims to halt the inflammation process and promotes repair of disease-related defects. Current regenerative procedures offers a limited potential toward attaining a complete periodontal res...

Open access Research Article 10.9734/jpri/2021/v33i54B33785

Advanced Physiotherapy of Supracondylar Femur Fracture with Implant In situ: A Case Report

Shraddha Kochar, Mitushi Deshmukh & Neha Chitale · Journal of Pharmaceutical Research International · 2021

Patient main concerns were restriction of movements of right knee and pus discharge from wound over right knee. In this case, the main clinical findings were a substantial loss in range of motion at right knee joints. There was also fixed flexion deformity seen over right knee. D...

Open access Research Article 10.9734/jpri/2021/v33i54B33791

Circadian Dysregulation: A Mainstream Mess of the Present World

Pankaj Mehta, Gurpreet Kaur, Neelam Thakur & Navneet Kaur · Journal of Pharmaceutical Research International · 2021

The physiological systems of humans and other organisms are periodic in nature. One such system is a circadian rhythm, a biological internal clock that is endogenous and entrainable. The circadian rhythm regulates essential functions such as the sleep/wake cycle, hormones, feedin...

Open access Research Article 10.9734/jpri/2021/v33i54B33786

Child Birth and its Effect on Functional Status of Women: A Review

T. R. Rejisha, Madhu Malleshappa, Ali Irani, Sruthy Johny & Jessy Grace · Journal of Pharmaceutical Research International · 2021

Though highly satisfying motherhood comes with its own challenges. Often underestimated, the effect of child birth on maternal function is a huge and can invariably effect not only the individual but the society in general. Yet there seems to be an attitude of “its all part and p...

Open access Research Article 10.9734/jpri/2021/v33i54B33788

A Review on Impact of Anthropogenic Sulphur Dioxide Pollution on Health and Environment

Pankaj Mehta, Jennifer Ngangbam, Neelam Thakur & Navneet Kaur · Journal of Pharmaceutical Research International · 2021

The explosive global change in the emissions of Sulphur dioxide (SO2) over the decades have brought about tremendous effects in the regional as well as global scale in the composition and quality of air that we breathe. The global SO2 emission peaked in the 1970s, decreased until...

Open access Research Article 10.9734/jpri/2021/v33i54B33796

Ginsenoside Re, Produces Multi-targeted Potent Antidiabetic Effects Via Estrogen Receptor Signaling Pathway in Rat, an Alternative Multi-Targeted Therapeutic for Type 2 Diabetes

Jingxian Gao, Xianli Meng, Bayin Zabu, Yi Zhang, Siqinbilig Wu, Huhe Muren, Ni Ha, Qinnuan Sun, Tang Jisi & Changxi Bai · Journal of Pharmaceutical Research International · 2021

Aims: To identify more effective ginsenoside for type 2 diabetes (T2D) and clarify whether the ginsenoside characterizing estrogenic multi-targeted antidiabetic effects. Study Design: Identifying more effective ginsenoside through preclinical evaluation of antidiabetic effects of...

Open access Research Article 10.9734/jpri/2021/v33i54B33782

'Silymarin' a Potential Treatment Targeting Hepatic Fibrosis of Schistosomiasis

Maimonah Alghanmi & Aziza Alrafiah · Journal of Pharmaceutical Research International · 2021

Background: Despite all treatment and control efforts, schistosomiasis still thrives in humanity. It is endemic in 78 countries that are anchored by poverty and diseases. Until now, the broad-spectrum praziquantel (PZQ) drug is the only effective treatment of choice. However, rep...

Open access Research Article 10.9734/jpri/2021/v33i54B33783

Isolation and Characterization of Quercetin from Bambusa arundinacea

Akanksha Awasthi, Divya Juyal, Mamta F. Singh & Saurabh Sharma · Journal of Pharmaceutical Research International · 2021

Flavonoids are natural antioxidants that are formed from plants and found in meals such as fruits and vegetables. They have the capacity to bind to free radicals. Because of its abundant prevalence in foods, Quercetin, which belongs to the flavonol subclass of flavonoids, has got...

Open access Research Article 10.9734/jpri/2021/v33i54B33784

Community Members and Dentist Perceptions for Oral Treatment Seeking Behavior in an Underprivileged Area: A Qualitative Study

Sarah Moideen, Farzeen Tanwir, Saima Mazhar, Natasha Zaidi, Chander Kumar & Arsalan Khalid · Journal of Pharmaceutical Research International · 2021

Background: Antibiotic resistance affects generations. It is a major health issue. Resistance to antibiotics is on the rise globally. The absence of proper regulatory mechanism and free access to pharmaceutical agents have led to self-medication and inappropriate therapeutic and...

Open access Research Article 10.9734/jpri/2021/v33i54B33787

Open VS Closed Techniques for Laparoscopic Abdominal Surgeries

Obaid Ul Haseeb, Haris Rashid, Afrin Ahmed, Mir Arsalan Ali, Shakil Alam, Santosh Kumar Sidhwani & Fatima Zehra Khan · Journal of Pharmaceutical Research International · 2021

Background: Laparoscopic surgery or "minimally invasive" surgery is a type of specialist surgery. The most crucial, demanding, and risky part of the laparoscopy is the creation of pneumoperitoneum. The two most prevalent methods for creating a pneumoperitoneum are the closed and...

Open access Research Article 10.9734/jpri/2021/v33i54B33789

Prescription Audit and Dispensing Errors in the Outpatient Pharmacy of Tertiary Care Multispecialty Teaching Hospital

T. Irsath Ahamed, K. Vaishnavi, R. R. Harini, Likhita Yalavarthi & Jagadeesan M. · Journal of Pharmaceutical Research International · 2021

Background: Although errors occurring during the process of dispensing may affect the goal of the treatment, they also can be the significant cause of morbidity and mortality. There are only few published evidences which focuses on the errors of dispensing that occurs in the phar...

Open access Research Article 10.9734/jpri/2021/v33i54B33790

The Outpatient Prescribing Pattern of Olopatadine in Al Saih

Nehad J. Ahmed, Gamal A. Gabr & Abeer A. El-Sherbiny · Journal of Pharmaceutical Research International · 2021

Aim: This study was conducted to demonstrate the prescribing pattern of olopatadine eye drops in Al Saih. Methodology: This is a retrospective study includes evaluating outpatient prescribing of olopatadine eye drops from 1st of January 2018 to 30th of June 2018 in a public hospi...

Open access Research Article 10.9734/jpri/2021/v33i54B33794

In-silico ADME and Docking-based Virtual Screening Study Aiming at the Sigma-Covalent Inhibition of SARS-CoV-2 RdRp

G. Koteswara Reddy, V. Nikhil Reddy, S. Phavethra, A. Bhavani, A. J. Vineeth & A. V. V. Satish Reddy · Journal of Pharmaceutical Research International · 2021

The objectives of the study were to examine the virtual screening of the compounds and sigma-covalent inhibition of SARS-CoV-2 RdRp (RNA-Dependent RNA-Polymerase), which is conserved and is an essential enzyme for RNA transcription and replication of this virus. In this study, we...

Open access Research Article 10.9734/jpri/2021/v33i54B33795

Evaluation of Diuretic activity of Fractional Extracts of Ajuga remota Benth (Lamiaceae) in Albino mice

Desalegn Chilo & N. J. Raju · Journal of Pharmaceutical Research International · 2021

The present study was evaluated the in vivo diuretic activity of fractional extracts of A. remota in albino mice. The dried aqueous crude extracts were subjected to soxhlet extraction by n-butanol, methanol and water solvents. The mice were randomly divided into eleven groups wit...

Open access Research Article 10.9734/jpri/2021/v33i54B33797

To Assess the Effectiveness of Selected Breathing Exercises among Chronic Obstructive Pulmonary Disease Patients

Archana Dhengare & Savita Pohekar · Journal of Pharmaceutical Research International · 2021

Mortality rate of chronic obstructive pulmonary disease (COPD) is more than 3 million people every year, making it 3rd largest cause of death in the world. It has been estimated that by the year 2030. chronic obstructive pulmonary disease will become the third biggest cause of de...

Open access Research Article 10.9734/jpri/2021/v33i54B33798