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All published articles 7450

Effect of Methotrexate and Linoleic Acid on BAX/BCL2 Ratio in Human Hepatocyte Cell

Ayse Gül Kabakci, Halil Mahir Kaplan, Ergin Şingirik & Memduha Gülhal Bozkır · Journal of Pharmaceutical Research International · 2021

Aims: To investigate the effect of methotrexate and linoleic acid on BAX/BCL 2 ratio in human hepatocyte cell. Study Design: Original Research Article. Place and Duration of Study: The study was carried out in partnership with the Department of Anatomy and Department of Medical P...

Open access Research Article 10.9734/jpri/2021/v33i60B34868

Preliminarily Phytochemical Screening, Anti Inflammatory and Antimicrobial Activity of Macrotyloma Uniflorum (Horse Gram) Leaf Ethanolic Extract on Selected Oral Pathogens

P. A. Vasishta, R. Gayathri & V. Vishnu Priya · Journal of Pharmaceutical Research International · 2021

Aim: To know the Preliminary phytochemical screening, Anti Inflammatory activity and antimicrobial activity Macrotyloma uniflorum (Horse gram) leaf ethanolic extract on selected oral pathogens. Introduction: Macrotyloma uniflorum also known as horse gram is a plant grown for feed...

Open access Research Article 10.9734/jpri/2021/v33i60B34870

Case Report on Congestive Cardiac Failure with Pneumonia with Bronchial Asthma

Chaitanya Gabhane, Manjusha Mahakarkar & Ruchira Ankar · Journal of Pharmaceutical Research International · 2021

Introduction: Congestive cardiac failure is a pathophysiologic state when the heart is not able to maintain its cardiac output to meet the demand of metabolizing tissues. Pneumonia is the inflammation of parenchyma of lungs. Bronchial Asthma is a diseases of airway produced by hy...

Open access Research Article 10.9734/jpri/2021/v33i60B34865

Prevalence and Factors Related to Metabolic Syndrome in Xo Dang Patients at Kon Tum General Hospital, Vietnam

Le Huu Loi, Dinh Thi Van Anh, Nguyen Quang Thieu, Cao Ba Loi, Nguyen Trong Hung & Phan Huong · Journal of Pharmaceutical Research International · 2021

Introduction: Metabolic syndrome (MetS) is a common disorder and different ethnicities may have different prevalence and related fators. MetS is associated with many chronic diseases and there is a great need for research on MetS in different ethnic groups, especially the communi...

Open access Research Article 10.9734/jpri/2021/v33i60B34872

A Comparative Study of the Effect of Propofol and Etomidate as an Induction Agent on Haemodynamic Changes during Induction and Endotracheal Intubation

Bhavini Shah & Shweta Birajdar · Journal of Pharmaceutical Research International · 2021

Aims: Presently Propofol and Etomidate are popular as rapid acting inducing agents. Due to reflex sympathetic stimulation, direct laryngoscopy and endotracheal intubation typically cause a cardiovascular stress response characterized by hypertension and tachycardia. This study is...

Open access Research Article 10.9734/jpri/2021/v33i60B34878

Anaesthetic Management of Left Cerebellopontine Angle Acoustic Nerve Schwannoma in Sitting Position with Intraoperative Electromyographic Facial Nerve Monitoring

Wankhade Prachi, Roshan Nisal, Swathi Reddy, Neeta Verma, Jui Jadhav & Nikhil Bhalerao · Journal of Pharmaceutical Research International · 2021

A case of left cerebellopontine angle acoustic nerve schwannoma in sitting position with electromyographic(EMG) monitoring for facial nerve was managed. The 40 year old male, ASA II, presented with complaints of difficulty in walking, left sided hearing loss, diminution of vision...

Open access Research Article 10.9734/jpri/2021/v33i60B34880

In-vitro Antibacterial Activity of Hydroethanolic Leaf, Stem, Root Extract of Acalypha indica - A Comparative Study

. Prithiksha, R. Gayatri Devi, J. Selvaraj & A. Jothi Priya · Journal of Pharmaceutical Research International · 2021

Background and Aim: Acalypha indica is a weedy, short lived and monoecious plant. It has an antioxidant effect and it must be implemented to control the disease where free radicals are involved. Acalypha plant is useful for the bronchitis, pneumonia, pulmonary tuberculosis patien...

Open access Research Article 10.9734/jpri/2021/v33i60B34882

Anticancer Potential of A. marmelos Fruit Extract in Human Colon Cancer Cell Lines is Mediated through the Regulation of EMT Signalling Molecules

Sheron Blessy, R. Gayatri Devi, J. Selvaraj & A. Jothi Priya · Journal of Pharmaceutical Research International · 2021

Background and Aim: A.marmelos is commonly called as Bael and is used as a medicinal plant mostly in the Ayurveda. Bael has the property of gastrointestinal effect. Bael phytochemicals are radioprotective, chemoprotective and it has efficacious properties in the treatment of canc...

Open access Research Article 10.9734/jpri/2021/v33i60B34884

Case Report on Intra Arterial Thrombosis

Sagar Anilrao Ingale, Darshana Kumari Wankhede & Sonali Kholhekar · Journal of Pharmaceutical Research International · 2021

Introduction: A thrombosis is a blood clot in an artery that can be highly harmful because it stops blood from reaching essential organs. Arteries are blood vessels that convey blood from the heart to the rest of the body and the heart muscle. Clinical Finding: pain in left lower...

Open access Research Article 10.9734/jpri/2021/v33i60B34885

Nutritional Composition, Mineral analysis and Sensory Evaluation of Cake and Chocolate with Moringa oleifera Leaf Powder

Santhadani Lenin, Ramasamy Sujatha & Shanmuga Sundaram · Journal of Pharmaceutical Research International · 2021

Moringa oleifera is a plant native to India that thrives in tropical and subtropical climates around the world. Moringa is commonly farmed around the world because it can resist both severe drought and moderate winter. The nutritional composition of dry M. oleifera leaf powder wa...

Open access Research Article 10.9734/jpri/2021/v33i60B34886

Case Report on Seizures Disorder

Prasad G. Gade, Manjusha Mahakarkar & Ruchira Ankar · Journal of Pharmaceutical Research International · 2021

Introduction:  Seizures are periods of aberrant motor, sensory, autonomic, or mental activity caused by discharge from brain neurons [1]. Epilepsy is defined as the two or more unprovoked seizures that occur more than 24 hours apart [2]. There are three types of seizures: focal,...

Open access Research Article 10.9734/jpri/2021/v33i60B34887

Mucormycosis with Ca Breast Cancer

Shivani R. Dethe, Priyanka Telang & Rupali Thorat · Journal of Pharmaceutical Research International · 2021

Mucormycosis is an extraordinary fungal contamination because organisms of Mucorales frequently happening in immunologically or diabetics compromised patients. Best case of number one Mucormycosis of breast is mentioned withinside in the English literature. We can explain another...

Open access Research Article 10.9734/jpri/2021/v33i60B34890

Modelling of the Rain Rate and Rain Attenuation for the Design of Line-of-Sight Link Budget over Warri, Delta State

E. R. Anaka, J. T. Zhimwang, O. S. Shaka & E. P. Ogherohwo · Journal of Pharmaceutical Research International · 2021

This paper presents the modeling of the rain rate and rain attenuation for the design of line-of-sight link budget. Rain rate data were collected from the Nigeria Meteorological Agency (NIMET) for Warri, Delta State (5.5540N 5.7930E). The rain rate data were collect for the perio...

Open access Research Article

Phytoconstituents and Medicinal Importance of Cannabis sativa

Anjali Thakur, . Sushma & Reena Sharma · Journal of Pharmaceutical Research International · 2021

Cannabis sativa has been reported that it is a widely spread species all over the world. It has been receiving more attention due to its therapeutic potential. Popularly, it is also known as marijuana. The phytoconstituents and characteristics of Cannabis sativa, stem, leaves and...

Open access Research Article 10.9734/jpri/2021/v33i60B34857

Spironolactone in Dermatology: A Mini Review

Jayakar Thomas, S. Soundarya & S. Vaishnavi · Journal of Pharmaceutical Research International · 2021

Spironolactone is a drug, similar in structure to aldosterone and acts as an aldosterone receptor antagonist with an anti-androgenic effect. This drug has proven to be useful in several dermatological entities, however its use has not been well explored. Its use in diseases such...

Open access Research Article 10.9734/jpri/2021/v33i60B34861