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Evaluation of Acute, Sub-Chronic Oral Toxicity Studies and Anti-Inflammatory Activity of Blumea mollis in Experimental Animals

Santosh Kumar, Phool Chandra & Munesh Mani · Journal of Pharmaceutical Research International · 2021

Objective: The goal of this study was to test the ethanol extract of the aerial part of the Blumea mollis (Asteraceae) for acute and sub-chronic toxicity as well as anti-inflammatory efficacy. Methods: The shade dried aerial part of Blumea mollis (0.5 kg) was powdered and extract...

Open access Research Article 10.9734/jpri/2021/v33i60B34988

The Effects of Plasma Exchange on Diffuse Alveolar Hemorrhage in Severe Vasculitis – A Case Study

Monali Rajendrakumar Sahu, Tanvi Dilip Wairagade, Sonali Dilip Wairagade, Ranjit S. Ambad & Parikshit Muley · Journal of Pharmaceutical Research International · 2021

Introduction: Rapidly progressive glomerulonephritis (RPGN) and widespread alveolar hemorrhage define ANCA-associated vasculitis (AAV), a rare, life-threatening illness (DAH). Case Presentation: An elderly female came with lower limb weakness and oliguria had features suggestive...

Open access Research Article 10.9734/jpri/2021/v33i60B35028

Knowledge, Awareness and Perception on Burning Mouth Syndrome among Dental Students-A Survey

Shifa Jawahar Ali, R. Gayathri & V. Vishnu Priya · Journal of Pharmaceutical Research International · 2021

Introduction: Burning mouth syndrome is a condition distinguished by painful burning sensation of the tongue and mucosal tissue of the mouth, lips and palate that lasts from a few days to a few months. Common symptoms of burning mouth syndrome include burning sensation in the mou...

Open access Research Article 10.9734/jpri/2021/v33i60B34991

Anaesthetic Management of Anaphylactic Shock Caused by ruptured Hydatid Cyst of the Liver: A Case Report

Akoijam Nikhil Singh, Neeta Verma & Sheetal Madavi · Journal of Pharmaceutical Research International · 2021

Hepatic hydatid disease is very common in developing nations. Although anaphylactic shock is a rare complication during anaesthesia, it can present with severe cardiovascular shock and hypersensitive reactions during surgical removal of hydatid cyst, requiring prompt emergency ma...

Open access Research Article 10.9734/jpri/2021/v33i60B34992

The Impact of Proton Pump Inhibitor Therapy on Outcomes in COVID-19 Patients: A Retrospective, Multicenter Study

Abdulhadi M. Alqahtani, Saja H. Almazrou, Khaled Alqahtani, Pendo Ntinika, Mohammed Alshahrani, Basmah F. Alqahtani, Amin K. Khattab, Sheikhah A. Alyahya, Fahad Dakilallah Aljohani & Hossein M. Elbadawy · Journal of Pharmaceutical Research International · 2021

Background:  Proton pump inhibitor (PPI)–coated prodrugs remain inactive until they enter the alkaline atmosphere of the duodenum, where they are absorbed and transmitted to parietal cells. This study aimed to evaluate the impact of PPI medication on patients with coronavirus dis...

Open access Research Article 10.9734/jpri/2021/v33i60B34994

Analytical Method Development and Validation for Simultaneous Estimation of Amlodipine Besylate and Indapamide by using UV VIS Spectrophotometry and RPHPLC in Bulk and Dosage Form

T. Prasanna Kumari, B. Tharun Kumar & Narender Malothu · Journal of Pharmaceutical Research International · 2021

The objective of this study was to develop a rapid and sensitive UV spectroscopic and RP-HPLC method for the analysis of Amlodipine Besylate and Indapamide in bulk drug and pharmaceutical dosage form by using the most commonly employed C-18 column with UV-detection. Acetonitrile:...

Open access Research Article 10.9734/jpri/2021/v33i60B34998

Predictive Model of Coronavirus Disease COVID-19 Cutting Edge Research

Sanket Santosh Gapat, Komal Meshram & Praful Patil · Journal of Pharmaceutical Research International · 2021

COVID19 is a global pandemic spread to over 170 nations and regions. In virtually all nations impacted, the number of illnesses and fatalities has skyrocketed. Predictive approaches may be implemented to aid in developing improved plans and the making of sound judgments. These te...

Open access Research Article 10.9734/jpri/2021/v33i60B35001

Evaluation of Intermental Foramina Distance among South Indian Population

S. Jeeva & Lavanya Prathap · Journal of Pharmaceutical Research International · 2021

Background: The intermental foramina distance varies between ethnicities, according to an OPG (orthopantomogram), which is a form of dental x-ray. The mandibular foramen has a bony canal developed in the mandible at two independent anatomies and its rim is 'v' shaped, that was it...

Open access Research Article 10.9734/jpri/2021/v33i60B35002

A Retrospective Study on Identification of Anterior Loop Pattern of Mental Nerve Entry into Mental Foramen in Digital Orthopantomography among South Indian Population

M. Srithika & Lavanya Prathap · Journal of Pharmaceutical Research International · 2021

Background: In the premolar location of mandible, the mental nerve's entry into the mental foramen pattern is a significant landmark. Different patterns of mental nerve entrance have been discovered. The current experiment was attempted to detect the different entry routes of the...

Open access Research Article 10.9734/jpri/2021/v33i60B35010

Ultra Violet and Visible Light as Therapeutic Tools for COVID-19

V. Masilamani, R. Vidhya Shree, Wafa M Al-Saleh & Lilia Coronato Courrol · Journal of Pharmaceutical Research International · 2021

Covid-19 is a disease which has become pandemic because of transmission of the tiny, single stranded virus, called SARS-CoV-2 or SARS-2.  It has infected so far 168 million people with a death toll of 3.6 million in 210 countries. The world has seen worse pandemics but this COVID...

Open access Research Article 10.9734/jpri/2021/v33i60B35019

A Short Note on Netarsudil

S. Padmaja & R. Srivignesh · Journal of Pharmaceutical Research International · 2021

Glaucoma currently affects over 60 million people worldwide and also one of the leading cause of irreversible blindness. Early Medical intervention is the preliminary therapy to prevent the progression of optic nerve damage and vision loss by reducing the Intra Ocular Pressure (I...

Open access Research Article 10.9734/jpri/2021/v33i60B34982

Significance of Microalgae Biotechnology: Production of Omega-3 Microbial Oils from Marine Thraustochytrids

Sonal Setya & Avneet Kaur · Journal of Pharmaceutical Research International · 2021

Thraustochytrids are multicellular fungal-like aquatic protists that originate all over the ocean. They're renowned for producing higher-value omega-3 polyunsaturated dietary fats (-3-PUFAs), such as docosahexaenoic acids (DHA), along with hydrolytic enzymes. Omega-3 dietary fats...

Open access Research Article 10.9734/jpri/2021/v33i60B34944

Acute Fatty Liver of Pregnancy-a Rare but Potentially Catastrophic Cause of Jaundice in Pregnancy

Sharmeen I. Memon & Neema S. Acharya · Journal of Pharmaceutical Research International · 2021

A 27-year-old female primigravida at 36.2 weeks gestational age presented nausea, vomiting, and yellowish discoloration of the eyes. On investigation, she had deranged liver and kidney functions, and USG was suggestive of Coarse Echotexture of the Maternal liver. We diagnosed it...

Open access Research Article 10.9734/jpri/2021/v33i60B34976

Effects of Genetically Modified Animals on Human Activities and Ecosystem

Neelkant Prasad & Manvi Singh · Journal of Pharmaceutical Research International · 2021

The first transgenic animals was mice which are now still the transgenic organisms most commonly used. There are various strategies in place for transferring foreign genes to the specific organisms. Transgenic organisms were used to study the gene and biological functions primari...

Open access Research Article 10.9734/jpri/2021/v33i60B34954