Skip to content
Research Article Open access CC BY 4.0

The Effect of Denitrification in the Human Dental Biofilm on Oral Tissues

Luay Thanoon Younis, Mohamed Ibrahim Abu Hassan, Tara Bai Taiyeb Ali

Journal of Advances in Medicine and Medical Research · pp. 1–5 · Published 3 Dec 2016

10.9734/BJMMR/2017/29816

Abstract

Global oral health surveys reveal that periodontal disease and dental caries affect human populations throughout the world. Denitrification plays both positive and negative roles in these disease processes by producing by-products that alter the oral environment, change the oral ecological balance, and the oral tissue immune response. Nitrate reduction may have a detrimental effect on the tooth supporting structures if the by-products of reduction are not neutralized. However, the nitrogen oxide by-products are beneficial in reducing dental caries. In this paper, we review the process of denitrification and its effect on the oral tissues.

Denitrification salivary nitrate dental caries periodontal disease

References (17)

  1. 1 Nitric oxide and the immune response [DOI]
  2. 2 Formation of nitric oxide-derived inflammatory oxidants by myeloperoxidase in neutrophils [DOI]
  3. 3 Dental biofilms: difficult therapeutic targets [DOI]
  4. 4 Influence of dietary nitrate on nitrite content of human saliva: Possible relevance to in vivo formation of N-nitroso compounds [DOI]
  5. 5 Multiple pathways of peroxynitrite cytotoxicity [DOI]
  6. 6 Evaluation of bacterial nitrate reduction in the human oral cavity [DOI]
  7. 7 Nitrates, nitrites and gastric cancer in Great Britain [DOI]
  8. 8 Protective effects of mercaptoethylguanidine, a selective inhibitor of inducible nitric oxide synthase, in ligature‐induced periodontitis in the rat [DOI]
  9. 9 Salivary contribution to exhaled nitric oxide [DOI]
  10. 10 Nitric oxide synthesis is increased in periodontal disease [DOI]
  11. 11 Denitrification in human dental plaque [DOI]
  12. 12 A multifaceted molecule, nitric oxide in oral and periodontal diseases [DOI]
  13. 13 Nitric oxide synthesis is decreased in periodontitis [DOI]
  14. 14 Evidence for Reactive Nitrogen Species Formation in the Gingivomucosal Tissue [DOI]
  15. 15 Nitric Oxide Concentrations in Saliva and Dental Plaque in Relation to Caries Experience and Oral Hygiene [DOI]
  16. 16 Nitrogen Dioxide-Dependent Oxidation of Uric Acid in the Human Oral Cavity under Acidic Conditions: Implications for Its Occurrence in Acidic Dental Plaque [DOI]
  17. 17 Production of nitric oxide-derived reactive nitrogen species in human oral cavity and their scavenging by salivary redox components [DOI]

Cited by 0

No indexed citations yet.

Article metrics

Real usage data collected on this platform.

66

Page views

0

PDF downloads

18

Outbound clicks

0

Citations

Views over time

Views by country

Approximate, from request IP at view time — not citizenship or institution. Countries with fewer than 5 views are grouped as "Other".

Traffic sources

Referring site, by host.

Views and downloads exclude known bots/crawlers. Citations combines this platform's own DOI-resolved index with each external source's own reported total — see Cited by above for individually listed citing works. Last refreshed 0 seconds ago.