Short Review of Sulphites as Food Additives
Alvaro R. Garcia-Fuentes, Sabrina Wirtz, Ellen Vos, Hans Verhagen
European Journal of Nutrition & Food Safety · pp. 113–120 · Published 23 Feb 2015
10.9734/EJNFS/2015/11557Abstract
Sulphites or sulphiting agents refer to sodium hydrogen sulphite, sodium metabisulphite, potassium metabisulphite, calcium sulphite, calcium hydrogen sulphite, and potassium hydrogen sulphite. As food additives, they are widely used by the food industry with a variety of commercial uses in food and beverages. Sulphites are effective bleaching agents, antimicrobials, oxygen scavengers, reducing agents, and enzyme inhibitors. Wine, beer, dehydrated fruits and vegetables, jam, juice, sugar, processed potatoes, seafood, meat and baked products are some of the food categories in which sulphites are added. Sulphites have been implicated in various health related issues. Asthmatic reactions and some antinutritional consequences such the degradation of thiamine (vitamin B1) are adverse reactions associated with sulphites. In many countries, sulphites have been regulated. Sulphites are generally recognized as safe in the USA with some exceptions when using in raw fruits and vegetables. In the European Union sulphites are also controlled, and the permitted amount varies according to the food product.
References (33)
- 1 Enzymatic browning reactions in apple and apple products [DOI]
- 2 Inhibition of enzymatic browning in foods and beverages [DOI]
- 3 Clinical effects of sulphite additives [DOI]
- 4 Sulfite Hypersensitivity. A Critical Review [DOI]
- 5 A review of sulphites in foods: Analytical methodology and reported findings [DOI]
- 6 Genetic effects of bisulfite (sulfur dioxide) [DOI]
- 7 Sulphite toxicity: A critical review of in vitro and in vivo data [DOI]
- 8 Inborn errors of molybdenum metabolism: combined deficiencies of sulfite oxidase and xanthine dehydrogenase in a patient lacking the molybdenum cofactor. [DOI]
- 9 Determination of sulfite with emphasis on biosensing methods: a review [DOI]
- 10 Chemical interactions between additives in foodstuffs: a review [DOI]
- 11 Hepatic Sulfite Oxidase [DOI]
- 12 Determination of free, bound and total sulphites in foods by indirect photometry-HPLC [DOI]
- 13 The mutagenic specificity of sodium bisulfite [DOI]
- 14 Cytogenetic damage induced in human lymphocytes by sodium bisulfite [DOI]
- 15 The toxicity of sulphite. I. Long-term feeding and multigeneration studies in rats [DOI]
- 16 Sulphiting agents in foods: Some risk/benefit considerations [DOI]
- 17 Chemistry of sulphiting agents in food [DOI]
- 18 Estimate of intake of sulfites in the Belgian adult population [DOI]
- 19 Inhibition of enzymatic browning in actual food systems by the Maillard reaction products [DOI]
- 20 Species variability in plasma S-sulfonate levels during and following sulfite administration [DOI]
- 21 Nutritional aspects of food preservatives [DOI]
- 22 The mutagenic action of sodium bisulfite [DOI]
- 23 The toxicity of sulphite. II. Short- and long-term feeding studies in pigs [DOI]
- 24 A sulphite-oxidase-deficient rat model: Subchronic toxicology [DOI]
- 25 Reactions of oxidation intermediates of sulphite species with some cellular components of plants [DOI]
- 26 Reaction of nitric oxide and its derivatives with sulfites: A possible role in sulfite toxicity [DOI]
- 27 Effect of Sodium Metabisulphite on Blood Metabolic Status of Wistar Rats [DOI]
- 28 Carcinogenicity test of potassium metabisulfite in mice [DOI]
- 29 Alteration of drug metabolizing enzymes in sulphite oxidase deficiency [DOI]
- 30 Nature and histogenesis of sulfite-induced gastric lesions in rats [DOI]
- 31 Metabolism and elimination of sulphite by rats, mice and monkeys [DOI]
- 32 Toxicology of sulphiting agents I: Animal studies [DOI]
- 33 Sulfites and foods, toxicity and hypersensitivity.
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