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Research Article Open access CC BY 4.0

Respiratory Tract Infections in Children Infected with HIV/AIDS in Minna, Niger State, Nigeria

O. O. Kolo, M. Galadima, S. Y. Daniyan, M. E. Abalaka

Microbiology Research Journal International · pp. 554–559 · Published 23 May 2015

10.9734/BMRJ/2015/17108

Abstract

Children with HIV/AIDS compared to immune competent ones develop respiratory tract infections in a pattern that are different in nature, severity and/or frequency. 50 children with laboratory confirmed HIV infection and 80 children with laboratory confirmation of HIV negative status were included in this study. Their ages ranged from 6 years to 14 years. All the patients were from urban areas. The study was aimed at determine the spectrum of bacterial agent that causes respiratory tract infection among HIV infected children as well as HIV uninfected children in Minna, Niger State and comparing the prevalence rate within different range of CD4 count. Sputum culture was taken to determine the profile of bacterial infection. All isolates from the cultures were identified using microbact identification kit (source: Oxoid Limited, United Kingdom). The frequency of bacteria isolates from HIV seropositive children was higher than the pneumoniae isolates from HIV Sero-negative Streptococcus pneumoniae 15(89%) and Klebsiella pneumonia20(89%) was the most common Gram-positive and Gram-negative bacteria identified respectively. 30% of the studied children were positive for at least one pathogenic bacterium. There was no significant difference between the prevalence rate of respiratory tract infection among HIV infected children and uninfected children and the rate of infection among children with CD4 count less than 100cell/ul was found to be significantly higher than those with higher CD4 counts at p level < 0.05.

Respiratory children infection Immunosuppression and HIV

References (12)

  1. 1 CD4+ T Cell Depletion during all Stages of HIV Disease Occurs Predominantly in the Gastrointestinal Tract [DOI]
  2. 2 Bacteremia among Children Admitted to a Rural Hospital in Kenya [DOI]
  3. 3 District Laboratory Practice in Tropical Countries, Part 1
  4. 4 Incidence of Opportunistic and Other Infections in HIV-Infected Children in the HAART Era [DOI]
  5. 5 Effect of age, polymicrobial disease, and maternal HIV status on treatment response and cause of severe pneumonia in South African children: a prospective descriptive study [DOI]
  6. 6 Increased Disease Burden and Antibiotic Resistance of Bacteria Causing Severe Community-Acquired Lower Respiratory Tract Infections in Human Immunodeficiency Virus Type 1-Infected Children [DOI]
  7. 7 Pulmonary Complications of HIV Infection [DOI]
  8. 8 High incidence of antimicrobial resistant organisms including extended spectrum beta-lactamase producing Enterobacteriaceae and methicillin-resistant Staphylococcus aureusin nasopharyngeal and blood isolates of HIV-infected children from Cape Town, South Africa [DOI]
  9. 9 Changing Global Epidemiology of Pulmonary Manifestations of HIV/AIDS [DOI]
  10. 10 Effect of cotrimoxazole on causes of death, hospital admissions and antibiotic use in HIV-infected children [DOI]
  11. 11 A Controlled Trial of Intravenous Immune Globulin for the Prevention of Serious Bacterial Infections in Children Receiving Zidovudine for Advanced Human Immunodeficiency Virus Infection [DOI]
  12. 12 Strategies for prevention of mother-to-child transmission of HIV [DOI]

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