Physicochemical Characterization of Iron Oxide Nanoparticle Coated with Chitosan for Biomedical Application
Tarfi Aziz, Shah Md. Masum, Md. Rakibul Qadir, Abdul Gafur, Dilruba Huq
International Research Journal of Pure and Applied Chemistry · pp. 1–9 · Published 1 Jan 2016
10.9734/IRJPAC/2016/23408Abstract
Aims: Synthesize and characterize a bio-polymer coated iron oxide nanoparticle, which has the potency to be used as an appropriate biomaterial for biomedical purpose. Magnetic iron oxide nanoparticles (MNPs) with biological coating exhibits many properties that can be exploited in a variety of biomedical applications. Place and Duration of Study: The study was performed at Bangladesh Council of Scientific and Industrial Research (BCSIR), Dhaka, Bangladesh from August 2013 to August 2014. Methodology: This research work describes the in-situ synthesis of chitosan-coated magnetic nanoparticles (CS MNPs) by co precipitation method where trisodium phosphate is added as ionic cross-linker. Analytical characterization of synthesized nanoparticles was performed using X-Ray Diffraction (XRD), Fourier Transform Infrared Spectroscopy (FTIR), Thermal gravimetric analysis (TGA) and Scanning Electron Microscope (SEM). Results: The XRD analysis proved that the synthesized iron oxide was magnetite (Fe3O4). The layer of chitosan on the magnetite surface was confirmed by FTIR. SEM image demonstrated a comparable morphology. The average diameter of synthesized nanoparticle was found to be 13.4 nm from XRD crystallite size analysis. TGA result indicated that the chitosan content of CS MNP were 29% by weight. Conclusion: The synthesized MNPs have many potential applications in biomedicine including targeted drug delivery, magnetic resonance imaging (MRI), and magnetic hyperthermia.
References (17)
- 1 Synthesis and surface engineering of iron oxide nanoparticles for biomedical applications [DOI]
- 2 The preparation of magnetic nanoparticles for applications in biomedicine [DOI]
- 3 Magnetic nanoparticle design for medical diagnosis and therapy [DOI]
- 4 Functionalisation of magnetic nanoparticles for applications in biomedicine [DOI]
- 5 Medical application of functionalized magnetic nanoparticles [DOI]
- 6 Collagen/chitosan porous scaffolds with improved biostability for skin tissue engineering [DOI]
- 7 Synthesis and characterization of surfactant-coated superparamagnetic monodispersed iron oxide nanoparticles [DOI]
- 8 Carbon Nanotube−Chitosan System for Electrochemical Sensing Based on Dehydrogenase Enzymes [DOI]
- 9 Surface-Modified Superparamagnetic Nanoparticles for Drug Delivery: Preparation, Characterization, and Cytotoxicity Studies [DOI]
- 10 Magnetic chitosan microspheres: preparation and characterization [DOI]
- 11 Magnetite Nanoparticles Prepared by Precipitation from Partially Reduced Ferric Chloride Aqueous Solutions [DOI]
- 12 Targeted Delivery of Multifunctional Magnetic Nanoparticles [DOI]
- 13 Formulation and characterization of amphotericin B–chitosan–dextran sulfate nanoparticles [DOI]
- 14 Degradation of covalently cross-linked carboxymethyl chitosan and its potential application for peripheral nerve regeneration [DOI]
- 15 Synthesis and characterization of Pluronic® grafted chitosan copolymer as a novel injectable biomaterial [DOI]
- 16 Preparation and characterization of magnetic nanoparticles with chitosan coating [DOI]
- 17 Infrared evolved gas analysis during thermal investigation of lanthanum, europium and samarium carbonates [DOI]
Cited by 30
Alexandre Adam, D. Mertz · Nanomaterials · 2023
W. O. Nyang’au, Tamara Kahmann, T. Viereck · Chemosensors · 2021
Tuba Tarhan · Turkish journal of chemistry · 2021
Jorge Suárez, Viviana B. Daboin, G. Gonzalez · International Journal of Biological Macromolecules · 2020
S. Mngadi, Seipati Rosemary Mokhosi, Moganavelli Singh · Inorganic Chemistry Communications · 2019
Osama Abu Noqta, A. Aziz, A. Usman · Solid State Phenomena · 2019
M. Akram, M. F. Alam, Han Ji · IOP Conference Series: Materials Science and Engineering · 2019
P. Nehra, R. Chauhan, N. Garg · British Journal of Biomedical Science · 2018
Ling Yan, Yi Xiang, Jia Yu · ACS Applied Materials and Interfaces · 2017
Tomy J. Gutiérrez, V. Álvarez · 2018
Showing 15 of 30 known citations — external sources report more than can currently be individually listed.
Related research
- Susceptibility of Some Clinically Resistant Bacterial Isolates to Thyme Essential Oil, Chitosan and Lactobacillus reuteri — shares topic coverage
- Effects of Addition of TiO2 Edible Coatings and Storage Periods on the Chicken Eggs Quality — shares topic coverage
- Gelatin, Chitosan, and Beeswax Based Edible Packaging for Food Product: A Review — shares topic coverage
- Functional Edible Coating from Banana Peel Starch (Musa sapientum L.) and Vannamei Shrimp Shell Chitosan for Quality Maintenance of Tomato — shares topic coverage
- Effect of the Different Surface Coatings and Packaging Materials for Shelf Life and Quality of Guava (Psidium guajava L.) CV. Allahabad Safeda — shares topic coverage
Article metrics
Real usage data collected on this platform.
89
Page views
0
PDF downloads
40
Outbound clicks
30
Citations
Views over time
Views by country
Approximate, from request IP at view time — not citizenship or institution. Countries with fewer than 5 views are grouped as "Other".
Traffic sources
Referring site, by host.
Views and downloads exclude known bots/crawlers. Citations combines this platform's own DOI-resolved index with each external source's own reported total — see Cited by above for individually listed citing works. Last refreshed 0 seconds ago.