In-vitro Estimation of Phytochemicals & Flavonoids in Citrus sinensis & Study their Antimicrobial & Antioxidant Activity
A. Kumar, A. Mahajan, Z. Begum
Asian Journal of Advanced Research and Reports · pp. 90–98 · Published 17 Aug 2022
10.9734/ajarr/2022/v16i930503Abstract
Orange (C. sinensis) peel flavonoids have antibacterial, antioxidant, anticancer, anti-inflammatory, and antiviral effects. However, there is a scarcity of information in the literature about orange peels flavonoids. So, we estimated phytochemicals in hydro-methanolic extract of C. sinensis peel and flavonoids were separated by Column chromatography and confirmed with TLC and HPLC. After that we evaluated the antimicrobial, antioxidant and nitric oxide scavenging activity. The MIC value of flavonoids against E. coli, B. subtilis, S. aureus and P. aeruginosa is 19.40, 20.48, 12.45 and 21.44µg respectively. The IC50 value of flavonoids for antioxidant and Nitric oxide scavenging activity is 121.4 and 0.88µg respectively. In the current study, Citrus peel flavonoids were found to have antibacterial, antioxidant, and nitric oxide scavenging action in methanolic extracts. This study suggests that C. sinensis flavonoids could be exploited as an antibacterial and antioxidant source in the future.
References (23)
- 1 The growing use of herbal medicines: issues relating to adverse reactions and challenges in monitoring safety [DOI]
- 2 Antioxidants of Natural Plant Origins: From Sources to Food Industry Applications [DOI]
- 3 Flavanones: Citrus phytochemical with health‐promoting properties [DOI]
- 4 Evolution of the Knowledge of Free Radicals and Other Oxidants [DOI]
- 5 Terpenoids and Polyphenols as Natural Antioxidant Agents in Food Preservation [DOI]
- 6 Chemistry and Pharmacology of Citrus sinensis [DOI]
- 7 Antioxidant and antimicrobial activities and UPLC-ESI-MS/MS polyphenolic profile of sweet orange peel extracts [DOI]
- 8 Citrus Peel Flavonoids as Potential Cancer Prevention Agents [DOI]
- 9 Peel oils from three Citrus species: volatile constituents, antioxidant activities and related contributions of individual components [DOI]
- 10 Regulation of exercise blood flow: Role of free radicals [DOI]
- 11 Relationships among classifications of ayurvedic medicine diagnostics for imbalances and western measures of psychological states: An exploratory study [DOI]
- 12 Emanating the specialty clinical practices in Ayurveda: Preliminary observations from an arthritis clinic and its implications [DOI]
- 13 Decoding Aging: Understanding the Complex Relationship among Aging, Free Radicals, and GSH [DOI]
- 14 Antimicrobial and Anti-Biofilm Activities of Citrus sinensis and Moringa oleifera Against the Pathogenic Pseudomonas aeruginosa and Staphylococcus aureus [DOI]
- 15 Bioavailable Citrus sinensis Extract: Polyphenolic Composition and Biological Activity [DOI]
- 16 Efficacy and sustainability of natural products in COVID-19 treatment development: opportunities and challenges in using agro-industrial waste from Citrus and apple [DOI]
- 17 Health awareness and popularity of alternative medicines among people of Jamnagar town: A cross - sectional study [DOI]
- 18 PHYTOCHEMICAL ANALYSIS AND ANTIBACTERIAL ACTIVITY OF ORANGE (Citrus sinensis) PEEL
- 19 In Vitro Comparative Study of Antioxidant and Antibacterial Activity of Selected Dietary Plants [DOI]
- 20 Isolation And Purification Of Flavonoids From The Leaves Of Locally Produced Carica Papaya
- 21 Journal of Agricultural and Food Chemistry [DOI]
- 22 Journal of Food Science and Technology [DOI]
- 23 Oxidative Medicine and Cellular Longevity [DOI]
Cited by 1
A. D. Sasanti, W. Widanarni, S. Sukenda · Biodiversitas Journal of Biological Diversity · 2025
Related research
- Chemical Composition, Genotoxicity and Antimicrobial Activities of Dracocephalum kotschyi Boiss against OXA-48 Producing Klebsiella pneumoniae Isolated from Major Hospitals of Kurdistan Province, Iran — shares topic coverage
- Prevalence of Methicillin-resistant Staphylococcus aureus among Health Care Workers in Tripoli Hospital, Libya — shares topic coverage
- A Cross Sectional Study on Prevalence of Antibiotic Resistance and Role of Efflux Pumps in Fluoroquinolone Resistance by using Efflux Pump Inhibitors in Isolated Cultures from Poultry, Dairy Farms and MTCC Strains from Reservoirs — shares topic coverage
- Antibacterial Evaluation of Aqueous and Ethanol Extracts of Ocimum gratissimum and Carica papaya — shares topic coverage
- Barleria acanthoides Vahl. Mediated Green Synthesis of Silver Nanoparticles and their Antibacterial Activity — shares topic coverage
Article metrics
Real usage data collected on this platform.
58
Page views
0
PDF downloads
31
Outbound clicks
1
Citations
Views over time
Views by country
Approximate, from request IP at view time — not citizenship or institution. Countries with fewer than 5 views are grouped as "Other".
Traffic sources
Referring site, by host.
Views and downloads exclude known bots/crawlers. Citations combines this platform's own DOI-resolved index with each external source's own reported total — see Cited by above for individually listed citing works. Last refreshed 0 seconds ago.