Skip to content
Research Article Open access CC BY 4.0

Antioxidant, Hypoglycemic and Neuroprotective Activities of Extracts from Fruits Native to the Amazon Region: A Review

Klenicy Kazumy de Lima Yamaguchi, Anderson de Oliveira Souza

Biotechnology Journal International · pp. 9–31 · Published 22 Oct 2020

10.9734/bji/2020/v24i630119

Abstract

The Amazon forest has the largest biome on the planet, and it is estimated that only 16 to 20% of the identified animal, and plant biodiversity. Considering plant diversity, we will highlight the biological properties of the fruits extracts of Arecaceae, Caryocaraceae, Malvaceae, Myrtaceae, Sapindaceae, and Solanaceae’s families due to their significant biological actions. This review presents the antioxidant, glycemic control, and neuroprotective activities from ten fruit extracts distributed in six botanical families in the Amazon region. We obtained 801 publications (described from 2010 to 2020), of which 64 articles were selected by the benchmark previously chosen. The antioxidant effect was the dominant effect observed in the studies used for this review, followed by glycemic control and protective actions in neurons. This review provides a synopsis of the recent literature exploring the extracts from native fruits to the Amazon region that could efficiently prevent pathologies associated with oxidative stress, and cellular maintenance mechanisms. 

Amazonian extracts nutrient-rich food secondary metabolism biological activities.

References (23)

  1. 1 Fenóis totais e atividade antioxidante de cinco plantas medicinais [DOI]
  2. 2 Radicais livres: conceitos, doenças relacionadas, sistema de defesa e estresse oxidativo [DOI]
  3. 3 Chemical Composition and Antioxidant/Antidiabetic Potential of Brazilian Native Fruits and Commercial Frozen Pulps [DOI]
  4. 4 Neuroprotection by flavonoids [DOI]
  5. 5 The effect of ginger ( Zingiber officinale ) on glycemic markers in patients with type 2 diabetes [DOI]
  6. 6 Fish consumption on the Amazon: a review of biodiversity, hydropower and food security issues [DOI]
  7. 7 Simultaneous quantification of phenolic compounds in buriti fruit (Mauritia flexuosa L.f.) by ultra-high performance liquid chromatography coupled to tandem mass spectrometry [DOI]
  8. 8 Açai (Euterpe oleracea Mart.) pulp dietary intake improves cellular antioxidant enzymes and biomarkers of serum in healthy women [DOI]
  9. 9 Impairment of Lysosome Function and Autophagy in Rare Neurodegenerative Diseases [DOI]
  10. 10 Protocatechuic acid activates key components of insulin signaling pathway mimicking insulin activity [DOI]
  11. 11 The genus Astrocaryum (Arecaceae) [DOI]
  12. 12 Lower glycemic indices and lipid profile among type 2 diabetes mellitus patients who received novel dose of Silybum marianum (L.) Gaertn. (silymarin) extract supplement: A Triple-blinded randomized controlled clinical trial [DOI]
  13. 13 Modulation of oxidative stress, inflammation, autophagy and expression of Nrf2 in hippocampus and frontal cortex of rats fed with açaí-enriched diets [DOI]
  14. 14 O potencial das palmeiras tropicais no Brasil: acertos e fracassos das últimas décadas [DOI]
  15. 15 Neuroprotective Effects of Açaí (Euterpe oleracea Mart.) against Rotenone In Vitro Exposure [DOI]
  16. 16 Clinical Marker of Platelet Hyperreactivity in Diabetes Mellitus [DOI]
  17. 17 Obtaining and characterization of anthocyanins from Euterpe oleracea (açaí) dry extract for nutraceutical and food preparations [DOI]
  18. 18 Rethinking Neuroprotection in Severe Traumatic Brain Injury: Toward Bedside Neuroprotection [DOI]
  19. 19 HPLC-DAD profile of phenolic compounds, cytotoxicity, antioxidant and anti-inflammatory activities of the amazon fruit Caryocar villosum [DOI]
  20. 20 Antioxidative effect and phytochemical profile of natural products from the fruits of “babaçu” (Orbignia speciose) and “buriti” (Mauritia flexuosa) [DOI]
  21. 21 Neuroprotective Natural Molecules, From Food to Brain [DOI]
  22. 22 Phytochemical characterization and antioxidant properties of the wild edible acerolaMalpighia umbellataRose [DOI]
  23. 23 Reproductive biology of endemic Solanum melissarum Bohs (Solanaceae) and updating of its current geographic distribution as the basis for its conservation in the Brazilian Cerrado [DOI]

Cited by 19

Guaraná (Paullinia cupana Kunth), marapuama (Ptychopetalum olacoides Benth.), genciana (Gentiana lutea L.), quassia (Quassia amara L.) e suas propriedades: uma breve revisão

Fernando Augusto Morgado Ferreira, Bárbara Bragança Ferreira, Vitor Augusto Nascimento Bragança · Research, Society and Development · 2022

Extractivism and production chain system of Açai in the middle Solimões River (Amazon region)

Klenicy Kazumy de Lima Yamaguchi, Eldrinei Gomes Peres, Jadyellen Rondon e Silva · 2023

Can the Supplementation Diet With Caryocar villosum (Aubl.) Pers Extracts Influence the Behavioral and Metabolic Parameters of Drosophila melanogaster?

Maria Eduarda Silva Soares, Andrielle Adelina Teodoro de Jesus, Douglas Lisboa Ramalho · Archives of Insect Biochemistry and Physiology · 2025

Piranhea trifoliata extracts ameliorate muscular decline in Drosophila melanogaster exposed to Paraquat

Letícia P. de Alencar, Lorena L. da Costa, Douglas R. Lisboa · Archives of Insect Biochemistry and Physiology · 2022

Beneficial effects of Docosahexaenoic acid consumption on brain health: A mini-review

Jadyellen Rondon Silva, Isabella Cristina Prescilio, Klenicy Kazumy Lima Yamaguchi · Journal of Food Bioactives · 2024

Chemistry and biology of piquiá: Review

Diana França de Souza, Cristiana Nunes Rodrigues, Pâmella Buenos Aires Domingues · Revista Brasileira de Plantas Medicinais · 2022

Showing 8 of 19 known citations — external sources report more than can currently be individually listed.

Article metrics

Real usage data collected on this platform.

70

Page views

0

PDF downloads

25

Outbound clicks

19

Citations

Views over time

Views by country

Approximate, from request IP at view time — not citizenship or institution. Countries with fewer than 5 views are grouped as "Other".

Traffic sources

Referring site, by host.

Views and downloads exclude known bots/crawlers. Citations combines this platform's own DOI-resolved index with each external source's own reported total — see Cited by above for individually listed citing works. Last refreshed 0 seconds ago.