Antibacterial Activity of Lythrum salicaria against Multidrug-resistant Acinetobacter baumannii and Pseudomonas aeruginosa
Ertugrul Guclu, Hayriye Genç, Mustafa Zengin, Oguz Karabay
Annual Research & Review in Biology · pp. 1099–1105 · Published 24 Dec 2013
10.9734/ARRB/2014/7357Abstract
Aims: Multidrug-resistant Acinetobacter baumannii and Pseudomonas aeruginosa are extremely problematic pathogens. Treatment of hospital infections caused by these pathogens is very difficult. In this study, we aimed to investigate the antibacterial efficacy of a traditional medicinal plant, Lythrum salicaria against these problematic bacteria. Methodology: Liquid extract of L. salicaria was prepared in methyl alcohol. A total of 30 A. baumannii and 27 P. aeruginosa strains which had been isolated from hospitalized patients as a nosocomial pathogen was used. The antibacterial activity of test materials was assessed by agar well diffusion test method. Results: Mean inhibition zone diameter against P. aeruginosa and A. baumannii were found 16.09 mm (minimum 12 mm, maximum 20 mm) and 18.3 mm (minimum 10 mm, maximum 25 mm), respectively. Conclusion: L. salicaria extract showed good antibacterial activity against these pathogens. Further pharmacokinetic and pharmacodynamic studies are needed for topical and oral usage of this traditional plant as a drug against multidrug-resistant pathogens.
References (11)
- 1 Bad Bugs, No Drugs: No ESKAPE! An Update from the Infectious Diseases Society of America [DOI]
- 2 Federal Funding for the Study of Antimicrobial Resistance in Nosocomial Pathogens: No ESKAPE [DOI]
- 3 Antimicrobial effects of Finnish plant extracts containing flavonoids and other phenolic compounds [DOI]
- 4 Clinical and Economic Impact of Common Multidrug-Resistant Gram-Negative Bacilli [DOI]
- 5 Transfer of Multidrug-Resistant Bacteria Between Intermingled Ecological Niches: The Interface Between Humans, Animals and the Environment [DOI]
- 6 Antibiotic discovery in the twenty-first century: current trends and future perspectives [DOI]
- 7 Antimicrobial Activity of Certain Plants used in Turkish Traditional Medicine [DOI]
- 8 Bioactivity guided isolation of antimicrobial compounds from Lythrum salicaria [DOI]
- 9 Biological activity and microscopic characterization of Lythrum salicaria L [DOI]
- 10 Human Acyl-CoA: Cholesterol acyltransferase (hACAT)-inhibiting triterpenes from Lythrum salicaria L. [DOI]
- 11 Chemical disinfectants and antiseptics. Quantitative suspension test for the evaluation of basic bactericidal activity of chemical disinfectants and antiseptics. Test method and requirements (phase 1) [DOI]
Cited by 27
Diana Antonia Safta, Ana-Maria Vlase, Anca Pop · Antioxidants · 2025
Sujogya Kumar Panda, S. Buroni, S. S. Swain · Frontiers in Microbiology · 2022
Umaira Ahsan, F. Mushtaq, S. Saleem · Frontiers in Pharmacology · 2022
K. G. Dolma, Rachana Khati, A. Paul · Biology · 2022
Mackingsley Kushan Dassanayake, T. Khoo, J. An · Annals of Clinical Microbiology and Antimicrobials · 2021
J. Marques, Daniel Martin, A. Amado · Plants · 2021
Randa A. Abd-ElNasser, Mona H. Abdel-Rahim, M. Mahmoud · Bulletin of Pharmaceutical Sciences. Assiut · 2020
Y. S. Lyamin, Y. Fedorova, P. V. Kulpin · 2020
B. Shin, Woojun Park · Journal of Microbiology · 2017
J. Piwowarski, S. Granica, A. Kiss · Journal of Ethnopharmacology · 2015
Showing 14 of 27 known citations — external sources report more than can currently be individually listed.
Related research
- Characterization and Evaluation of the Antibacterial Activity of Silver Nanoparticles Synthesized by Green Method Using Phyllanthus emblica Leaf Extract — shares topic coverage
- Antibacterial and Phytochemical Activity of Gliricidia sepium against Poultry Pathogens — shares topic coverage
- Evaluation of Antibacterial Activity of Piper betel Leaves and Nigella sativa Seeds against Multidrug Resistant Food and Water Borne Pathogenic Bacteria: An in vitro Study Model — shares topic coverage
- Traditional and Molecular Identification of Bacterial Contamination from Honey (Processed and Unprocessed) and Their Control by Phytotherapy — shares topic coverage
- Antibacterial, Antioxidant Activity and Phytochemical Analysis of Euphorbia hirta Linn. — shares topic coverage
Article metrics
Real usage data collected on this platform.
14
Page views
0
PDF downloads
1
Outbound clicks
27
Citations
Views over time
Views by country
Approximate, from request IP at view time — not citizenship or institution. Countries with fewer than 5 views are grouped as "Other".
Traffic sources
Referring site, by host.
Views and downloads exclude known bots/crawlers. Citations combines this platform's own DOI-resolved index with each external source's own reported total — see Cited by above for individually listed citing works. Last refreshed 0 seconds ago.