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Journal of Advances in Medical and Pharmaceutical Sciences

Published by SCIENCEDOMAIN international · ISSN (electronic) 2394-1111

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890

Articles indexed

64

2026 articles

890

Open access

3,582

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Articles (890)

Basic Pharmacology of NG -Nitro – L – Arginine Methyl Ester

Muhanad S. Abdelwahab, Mukhallad A. M. Mohammed, H. M. Abdelwhab, Mazin S. Abdalla Mohamed & Mansour Abdelgader Bellal · Journal of Advances in Medical and Pharmaceutical Sciences · 2019

NG – Nitro- L- arginine methyl ester (L-NAME) is a synthetic drug in which a quanidino is substituted for L-arginine analoques. It is a competitive enzyme inhibitor which inhibits nitric oxide synthase, hence, decreasing nitric oxide production [1].

Open access Research Article 10.9734/JAMPS/2018/46307

Haematologic and Gastric Histological Changes Associated with Administration of Ground Nutmeg (Myristica fragrans) Seed on Adult Male Albino Wistar Rats

Christopher Chiedozie Mbadugha, Gabriel Donatus Edem, Uka Emmanuel & Isaac Etim Udoudo · Journal of Advances in Medical and Pharmaceutical Sciences · 2019

Introduction: Substantially unproven scientifically are numerous assumed health benefits of nutmeg, moreover, a few of the scientifically substantiated research done were on the nutmeg oil and the mace. There is paucity of data based on scientific protocol on research carried out...

Open access Research Article 10.9734/JAMPS/2018/46509

Dose-dependent Effect of Avocado Peel Hydroethanolic Extract on Antioxidant Status of Heart and Kidney Tissue Homogenates in Wistar Rats

Daniel Y. Onoja, Arthur N. Chuemere, Kolawole A. Tolunigba, Mobisson S. Kelechi & Ilochi N. Ogadinma · Journal of Advances in Medical and Pharmaceutical Sciences · 2019

This study evaluated the dose-dependent effect of avocado (Persea americana) peel hydroethanolic extract on antioxidant status of heart and kidney tissue homogenates in wistar rats. A total of 60 wistar rats were used and the study period lasted for 42 days. The animals were rand...

Open access Research Article 10.9734/JAMPS/2018/46358

Potential Hazards of Ethanolic Extract of Garcinia kola on the Testes of Adult Male Wistar Rats

E. O. Nweke, J. K. Opara & I. J. Okafor · Journal of Advances in Medical and Pharmaceutical Sciences · 2019

Background: Garcinia kola has been used in the treatment of a wide range of diseases and its importance in folkloric medicine is eminent. Aim: This study investigated the histological effect of ethanolic extract of G. kola on the testes of male Wistar rats. Materials and Methods:...

Open access Research Article 10.9734/JAMPS/2018/46524

Predictive Factors of Anaemia in Women in a Ghanaian Rural District

Dinah Asantewah Koranteng, Franklin Acheampong, Isaac Koranteng & Richard Adanu · Journal of Advances in Medical and Pharmaceutical Sciences · 2019

Background: Anaemia is a condition of public health concern worldwide especially in developing countries. Anaemia falls in the top ten causes of morbidity in Ghana with a nationwide prevalence of about 45%. A rural district (Shai-Osudoku District), close to the capital city in Gh...

Open access Research Article 10.9734/JAMPS/2018/46017

Functional Compounds of Lobelia inflata Revealed Novel Potential Targets for Chronic Cough Therapy

Toluwase Hezekiah Fatoki, Olusola Olalekan Elekofehinti, Afolabi Clement Akinmoladun & David Morakinyo Sanni · Journal of Advances in Medical and Pharmaceutical Sciences · 2019

Aim: To identify potential targets involved in chronic cough pathophysiology toward discovery and development of new therapeutants. Methodology: This work was carried out on bioactive compounds of selected medicinal plants with reference to known therapeutic agents using computat...

Open access Research Article 10.9734/JAMPS/2018/45276

Extracts of Ageratum Conyzoides L. Protects against Carbon Tetrachloride – Induced Toxicity in Rats through Inhibiting Oxidative Stress

Frederick Sarfo-Antwi, Christopher Larbie & Duduyemi Babatunde · Journal of Advances in Medical and Pharmaceutical Sciences · 2019

Aims: The present study was aimed at investigating the hepatoprotective and nephroprotective activities of 50% hydroethanolic leave extracts of the Ageratum conyzoides and fractions on carbon tetrachloride - induced hepatotoxicity in rats. Study Design: A total of 30 Sprague Dawl...

Open access Research Article 10.9734/JAMPS/2018/45189

Determination of Haematocrit, Erythrocyte Sedimentation Rate (ESR) and Methaemoglobin Levels in Municipal Solid Waste Collectors (Sanitation Workers) in Port-Harcourt, Nigeria

Onengiyeofori Ibama & Felix Eedee Konne · Journal of Advances in Medical and Pharmaceutical Sciences · 2018

Aim: This study was carried out to ascertain whether or not occupational exposure affects the haematocrit, erythrocyte sedimentation rate, and methaemoglobin levels of municipal solid waste (MSW) collectors. Methodology: A total of 60 male subjects were recruited for this study,...

Open access Research Article 10.9734/JAMPS/2018/46187

Impacts of Analogy and Dimerization of Bioactive Compounds on Molecular Biological Functions

Toluwase H. Fatoki, Oladoja A. Awofisayo, Olusola A. Ogunyewo, Harriet U. Ugboko & David M. Sanni · Journal of Advances in Medical and Pharmaceutical Sciences · 2018

Aim: To determine the effect of analogy and dimerization of bioactive compounds at the molecular level on the biological functions. Methodology: This work was carried out on a model set of bioactive compounds which consisted of resveratrol, piceatannol, isorhapontigenin, scirpusi...

Open access Research Article 10.9734/JAMPS/2018/45211