Kawasaki disease (KD) is an acute, self-limiting systemic vasculitis that predominantly affects children younger than 5 years and may involve the coronary arteries. In young infants, incomplete or atypical presentations may complicate early recognition, particularly when classica...
Open access
Research Article10.9734/ajpr/2026/v16i10578
Aims: To describe an infant in whom early-onset seizures led to the diagnosis of 1p36 deletion syndrome and to emphasise the diagnostic contribution of whole-exome sequencing with copy-number variation analysis when the early phenotype is incomplete. Presentation of Case: A 2-mon...
Open access
Research Article10.9734/ajpr/2026/v16i10577
Aims: To describe a paediatric case of spontaneous periodic hypothermia (Shapiro's syndrome) occurring in the absence of agenesis of the corpus callosum, and to review the relevant literature and diagnostic approach. Presentation of Case: A 2-year-and-9-month-old boy, previously...
Open access
Research Article10.9734/ajpr/2026/v16i10576
Aims: To describe cerebellar ataxia as a rare presenting manifestation of juvenile systemic lupus erythematosus (jSLE) and to emphasise the diagnostic value of associated systemic findings. Presentation of Case: An 11-year-old previously healthy girl presented with a facial erupt...
Open access
Research Article10.9734/ajpr/2026/v16i10575
Ikechukwu Agwu Francis, Ekemini Udo, Samuel Ibok, Idakari Nweke, Ifeanyi Onwuezobe, Chinedum Amagwu, Augusta Mgbedimma, Anozie Chikezie Enyinnaya & Agantem Emmanuel Ekuma·Asian Journal of Pediatric Research·2026
Background: Actinomycosis is a chronic suppurative infection caused by anaerobic Gram-positive Actinomyces species that normally colonise the oral cavity and digestive and urogenital tracts. Although cervicofacial disease is recognised, isolated labial involvement is uncommon, pa...
Open access
Research Article10.9734/ajpr/2026/v16i10574
Aims: To describe multiple presumed pyogenic liver abscesses developing shortly after appendectomy for acute appendicitis reported as uncomplicated in a child, and to highlight diagnostic uncertainty, portal venous findings, and management when drainage is considered unsafe. Pres...
Open access
Research Article10.9734/ajpr/2026/v16i10573
Aims: Congenital hypoparathyroidism is a rare cause of severe neonatal and early-infantile hypocalcaemia and may present with recurrent seizures. We report a case to highlight the importance of early metabolic evaluation in infants with unexplained recurrent seizures and to revie...
Open access
Research Article10.9734/ajpr/2026/v16i9588
Background: Urinary tract infections (UTIs) are among the most common bacterial infections in children, with Escherichia coli being a major causative pathogen. Urinalysis is a simple and accessible laboratory investigation that provides useful information about urinary abnormalit...
Open access
Research Article10.9734/ajpr/2026/v16i9572
Aims: To report an atypical phenotypic presentation of Lesch-Nyhan syndrome (LNS) revealed by isolated generalised hypotonia and growth retardation in the absence of the classical neurological and behavioural features, and to emphasise the importance of systematic serum uric acid...
Open access
Research Article10.9734/ajpr/2026/v16i9587
Chronic malabsorption in early childhood is commonly associated with gastrointestinal disorders such as coeliac disease, but overlapping clinical features may delay recognition of other systemic causes, including cystic fibrosis. This case report describes a 2½-year-old boy who p...
Open access
Research Article10.9734/ajpr/2026/v16i9571