Moussé Logbo Mathias

Identification of Novel Polyketide Synthase 13 of Mycobacterium Tuberculosis Inhibitors: A Modelling Approach Using the Pharmacophore Method -Based Virtual Screening

Djako Akassa Marius Bernard, Niaré Adama, Fofana Issouf, Moussé Logbo Mathias, Kéita Mélalie & Megnassan Eugène · Journal of Advances in Medical and Pharmaceutical Sciences · 2025

Tuberculosis is an infectious disease caused by Mycobacterium tuberculosis. It remains a major public health problem worldwide. In 2022, 10.6 million people contracted tuberculosis and 1.3 million died from it.  This manuscript presents our work, the aim of which is to find new i...

Open access Research Article 10.9734/jamps/2025/v27i6784

Molecular Modeling and Virtual Screening: Application to the Design of Benzoisoxazole-Derived Inhibitors for the Treatment of Prostate Cancer, Bromodomain-Containing Protein 4 (BRD4)

Kouadja Rika Justin, Kambiré Sobamfou Marius, Oyedele Sampson Oladapo, Niaré Adama, Gloua Sounkolé Marius & Moussé Logbo Mathias · Biotechnology Journal International · 2026

Bromodomain-containing protein 4 (BRD4) contributes to transcriptional regulation implicated in castration-resistant prostate cancer and is a candidate target for the design of small-molecule inhibitors. This study used molecular modelling and virtual screening to explore benzois...

Open access Research Article 10.9734/bji/2026/v30i6921