Y. Michotte

Mild Hypothermia Attenuates the Excitatory Amino Acids Overflow and Diminishes the Nitric Oxide Synthase Activity during Reperfusion after Asphyxial Cardiac Arrest in Rats

S. Hachimi-Idrissi, T. Zgavc, I. Smolders, S. Sarre, L. Huyghens & Y. Michotte · Journal of Advances in Medicine and Medical Research · 2013

Aims: Neurotransmitter overflow into the extracellular space and activation of nitric oxide synthase were implicated in neuronal death after cerebral ischemia. A small temperature reduction induced after the insult crucially mitigated the neuronal death. To elucidate the mechanis...