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Xiaoxiao Jia

Publications (6)

Application of High-concentration 35 kDa Hyaluronic Acid Fragment Gel in the Treatment of Mild Gingival Recession and Periodontal Inflammation: A Case Series

Mizhou Hui, Yihai Li, Xiaoxiao Jia, Jessica H Hui & Vera Gorbunova · Asian Journal of Dental Sciences · 2026

Background: Periodontal disease is a chronic inflammatory condition characterized by gingival redness and bleeding in its early stages, which can progress to gingival recession and tooth mobility in severe cases. Increasing evidence suggests that periodontal disease represents a...

Open access Research Article 10.9734/ajds/2026/v9i1296

Preliminary Clinical Observations on 35 kDa Low-Molecular-Weight Hyaluronan (HA35) in Influenza Prevention and Symptom Control: A Case Series

Jessica H. Hui, Xinyue Ma, Xiaoxiao Jia, Mizhou Hui & Li Liu · Asian Journal of Research in Infectious Diseases · 2025

Influenza is caused by influenza viruses, which infect host respiratory epithelial cells by binding the viral envelope hemagglutinin to sialic acid receptors on the cell surface. Hemagglutinin can induce red blood cell agglutination in vitro, a hallmark of viral infectivity. Our...

Open access Research Article 10.9734/ajrid/2025/v16i11501

Posterior Occipito-Cervical Liposuction Improves Mental Clarity and Prolongs Wakeful Working Time: Two Case Reports

Wenhai Ma, Weidong Xu, Xiaoxiao Jia, Mizhou Hui, Li Liu & Mingxing Ding · Asian Journal of Case Reports in Surgery · 2025

Background: Some middle-aged and older adults develop excess fat in the posterior occipito-cervical region—a transitional area between the back of the head and the upper posterior neck—often forming a visible hump. This condition is not only a cosmetic concern but is also linked...

Open access Research Article 10.9734/ajcrs/2025/v8i2682

The Low Molecular Weight Hyaluronan Fragment HA35 Serves as a Dual Antagonist of Pain-Related Calcium Channels TRPV1 and TRPA1

Xinyue Ma, Joshua Shofaro, Xiaoxiao Jia, Zhaohui Ma & Mizhou Hui · Journal of Pharmaceutical Research International · 2025

Background: Pain, especially chronic pain, remains a major health challenge worldwide. Transient receptor potential (TRP) channels, particularly TRPV1 and TRPA1, play crucial roles in pain perception. Hyaluronic acid (HA), whose bioactivity varies by molecular weight, has shown p...

Open access Research Article 10.9734/jpri/2025/v37i67702

Effectiveness and Safety of 35 kDa Hyaluronan for Symptom Relief in Advanced Lung Cancer: A Pilot Study Focusing on Pain and Cough

B. Sunjidmaa, Dylan Treger, Xiaoxiao Jia, Jessica Hui, Taivanbat Ganbaatar, Bat-erdene Ganbaatar, Zhaohui Ma & Mizhou Hui · Asian Oncology Research Journal · 2025

Background: Advanced lung cancer and its associated pain symptoms place a significant burden on patients. A 35 kDa hyaluronan fragment (HA35) has been confirmed to effectively alleviate inflammatory and neuropathic pain in palliative care settings. This single-arm, prospective pi...

Open access Research Article 10.9734/aorj/2025/v8i1101

Rapid Lymphatic Absorption of Orally Administered Low-Molecular-Weight Hyaluronic Acid: A Pathway to the Bloodstream via Mesenteric Nodes

Khandmaa Dashnyam, Joshua Shofaro, Jessica Hui, Xiaoxiao Jia & Mizhou Hui · Journal of Pharmaceutical Research International · 2025

Background: The 35 kDa low-molecular-weight hyaluronic acid (HA35) injection has shown efficacy in alleviating various types of pain, reducing inflammation and edema, and exhibiting potential in lipolysis and cosmetic applications. Compared to injectable forms, oral administratio...

Open access Research Article 10.9734/jpri/2025/v37i57698