Williams A. Nnenna

Neuroprotective Effect of Dacryodes edulis Ethanolic Leaf Extract on the Hippocampus of Rats of Ketamine-Induced Neurotoxicity

Sadeyeng E. Anani, Williams A. Nnenna, Eric A. Agaba, Nsikak M. Umoh, Ifiok F. Bassey, Eru M. Eru, Michael E. Oku, Kelechi C. Uruakpa, Paul A. Odey, Theresa E. Isamoh, Cletus U. Ajang, Gideon Uzor, Gabriel U. Udo-affah & Anozeng O. Igiri · Asian Journal of Research and Reports in Neurology · 2024

Introduction: The brain is an organ that is responsible for knowledge acquisition, cognition and control of body movements. Its normal functioning and structure can be affected by exposure to drugs of abuse (for example ketamine) which can cause disorder in the nervous system. Me...

Open access Research Article

Retrospective Analysis of Demographic Distribution of Dementia Cases from Federal Neuro-psychiatric Hospital in Calabar, Nigeria (2011–2021)

Eru Mba Eru, Theresa Ekpenyong Isamoh, Christabel Ojibima Francis, Williams A. Nnenna, E. Oku Michael, Onne Eru Mba, Eric Agim Agaba, Obinna Chukwuemeka Godfrey, Nwaguma Precious Chidinma & Anozeng O. Igiri · International Neuropsychiatric Disease Journal · 2026

Aims: The study aimed to investigate the demographic distribution of patients diagnosed with dementia from the Federal Neuro-psychiatric Hospital (2011-2021), Calabar, Cross River State. Study design: The retrospective research design was adopted for the study. This was done to...

Open access Research Article 10.9734/indj/2026/v23i2550

Ameliorative Effect of Curcuma longa Ethanolic Extract on the Histology, Hepatic Glycogen Content and Some Biochemical Parameters of the Liver in Streptozotocin-Induced Hyperglycemic Wistar Rats

Mfon I. Akpaso, Lydia E. Bassey, Sadeyeng E. Anani, Michael E. Oku, Williams A. Nnenna, Nsikak M. Umoh, Eru M. Eru, Elton N. Takim, Gideon Uzor, Theresa E. Isamoh & Eric A. Agaba · Journal of Complementary and Alternative Medical Research · 2024

Introduction: Diabetes mellitus is a life threatening disease that requires immediate medical treatment. Numerous medicinal plants have been known for their anti-diabetic effects and Curcuma longa (turmeric) is one of them. This attribute is possible due to the pharmacological pr...

Open access Research Article 10.9734/jocamr/2024/v25i11579

Effect of Alkaloid-rich Fraction of Dacryodes edulis Leaves on the Microstructure of the Hippocampus and Blood Glucose Levels of STZ-Induced Diabetic Wistar Rats

Eru, E.M, Theresa I. Ekpenyong, Cyril A. Agbor, Christie E. Fischer, Michael E. Oku, Samson O. Paulinus, Etim D. Isaiah, Kelechi C. Uruakpa, Williams A. Nnenna, Nsikak M. Umoh, Eric A. Agaba & Anozeng O. Igiri · International Neuropsychiatric Disease Journal · 2025

Aim: the aim of this study was to elucidate the effect of alkaloid-rich fraction of Dacryodes edulis on body weight, blood glucose level and the microanatomy of the hippocampus of STZ-induced Diabetic Wistar rats. Methodology: 25 adult male Wistar rats were used for the experimen...

Open access Research Article 10.9734/indj/2025/v22i3477

Neuroprotective Effect of Dacryodes edulis Ethanolic Leaf Extract on the Prefrontal Cortex and Long-term Learning and Memory in Wistar Rats of Ketamine-Induced Neurotoxicity

Sadeyeng E. Anani, Michael E. Oku, Eru M. Eru, Kelechi C. Uruakpa, Ifiok F. Bassey, Gabriel U. Udo-affah, Paul A. Odey, Eric A. Agaba, Theresa E. Isamoh, Williams A. Nnenna, Nsikak N Umoh, Cletus U. Ajang & Anozeng O. Igiri · Asian Journal of Research and Reports in Neurology · 2024

Introduction: Dacryodes edulis (African pear) is a medicinal plant known for its medicinal qualities. Its extracts are said to possess many health-promoting constituents such as antioxidants that have been used to treat many illnesses, including neurological disorders. Drug-induc...