William Yavo

Discovery of 5-Chlorobenzimidazole-based as Promising Inhibitors of Chloroquine-Resistant Plasmodium Strains: Synthesis, Biological Evaluation, Molecular Docking and Computational Studies

Jean Paul N’Guessan, Songuigama Coulibaly, Abdulrahim A. Alzain, Drissa Sissouma, William Yavo & Mahama Ouattara · Journal of Pharmaceutical Research International · 2021

Background: To overcome drug resistance to current antimalarial drugs, we propose the synthesis and in vitro evaluation of the antiplasmodial activity of a series of 5-chlorobenzimidazolyl-chalcones against chloroquino sensitive (CQ-S) and chloroquino resistant (CQ-R) strains of...

Open access Research Article 10.9734/jpri/2021/v33i46B32925

Evaluation of Cytotoxic Profile of Some Chalcone Derivatives with Antimalarial Properties

Marius Trésor Dable, Mahama Ouattara, Edgard Valéry Adjogoua, Konan Dominique Tano, Akissi Jeanne Koffi, Nkoua Badzi Cynthia & William Yavo · Chemical Science International Journal · 2020

Malaria continues to kill thousands of people worldwide. People South of the Sahara are paying the heaviest price for this epidemic. In addition, the resistance of Plasmodium falciparum which spreads to artemisinin derivatives becomes worrying. To respond to this emergency, the s...

Open access Research Article 10.9734/CSJI/2020/v29i430172

Mixed Plasmodium Species Infections and Malaria Susceptibility among Fulani, Lobi and Birifor Ethnic Groups in Bouna, Côte d’Ivoire

Mireille A Amiah, David T Okou, Paterne A Gnagne, Amadou Niangaly, Nouhoum Diallo, Abibatou Konaté-Touré, Simon-Pierre A N’Guetta & William Yavo · International Journal of TROPICAL DISEASE & Health · 2025

Background: Malaria remains a major health problem in sub-Saharan Africa. One of the main challenges that researchers are facing in eliminating the parasite is chemoresistance to antimalarial drugs. Resistance to artemisinin, the main molecule of drug combinations used in malaria...

Open access Research Article 10.9734/ijtdh/2025/v46i51655