Increased Complement Deposition on Red Blood Cells in Children with Sickle Cell Trait
Walter Otieno, Benson B. A. Estambale, Michael M. Odera, Collins O. Odhiambo, Joash R. Aluoch, Bernard Guyah, Stacey M. O. Gondi & José A. Stoute · Journal of Advances in Medicine and Medical Research · 2014
Aims: Immune-mediated mechanism, such as deposition of complement (C3b) on erythrocytes leading to enhanced receptor-mediated uptake by macrophages has been proposed to contribute partly to the destruction of non-infected cells leading to anaemia. The extent of complement deposit...
Open access
Research Article
10.9734/BJMMR/2015/9438