Virtual Design of Novel Coumarinyl-Substituted Sulfonamide Inhibitors of Carbonic Anhydrase II as Potential Drugs against Glaucoma
Eric Ziki, Ludovic Akonan, Koffi Charles Kouman, Brice Dali, Eugene Megnassan, Rita Kakou-Yao, Abodou Jules Tenon, Vladimir Frecer & Stanislav Miertus · Journal of Pharmaceutical Research International · 2023
Background: We have carried out virtual design of coumarinyl-substituted sulfonamides (CSAM) analogs as inhibitors of human carbonic anhydrase II (hCA II) endowed with favorable predicted pharmacokinetic profiles and potential therapeutic effects against glaucoma. Methods: modify...
Open access
Research Article
10.9734/jpri/2023/v35i247424