The Entrapment of Paclitaxel in PLGA Nanoparticles Increases its Cytotoxicity against Multiresistant Cell Line
Vanya Bojat, Vadim Balabanyan & Renad Alyautdin · Journal of Advances in Medicine and Medical Research · 2011
Paclitaxel (Ptx) is a taxane anticancer mitotic inhibitor, widely used in oncology for the last 20 years. Poor solubility of Ptx, as a consequence using of toxic solvents such as Cremofor EL, high affinity to P-glycoprotein are associated with serious side effects due to hypersen...
Open access
Research Article
10.9734/BJMMR/2011/382