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Uzozie Chikere Ofoego

0000-0002-0000-535X

Publications (8)

Hepatoprotective and Antiplasmodial Effects of Ethanolic Leaf Extracts of Azadirachta indica and Cymbopogon citratus in Plasmodium berghei-Infected Mice

Uzozie Chikere Ofoego, Prisca Isioma Afam, Amarachukwu Ndubuisi Ofoego, Princewill Sopuluchukwu Udodi & Chinyere Elizabeth Eze · Journal of Complementary and Alternative Medical Research · 2025

Malaria remains a major public health concern in sub-Saharan Africa, with Nigeria among the most affected countries. This study evaluated the hepatoprotective and antiplasmodial effects of ethanolic leaf extracts of Azadirachta indica (EAI) and Cymbopogon citratus (ECC) in Plasmo...

Open access Research Article 10.9734/jocamr/2025/v26i8692

Evaluation of the Hepatic Effects of Unripe Carica papaya (Pawpaw) Sap in Adult Male Wistar Rats

Uzozie Chikere Ofoego, Dumebi Success Nnaji, Amarachukwu Ndubuisi Ofoego, John Obinna Chukwudike & Ephraim Chinedu Nosike · Asian Journal of Advanced Research and Reports · 2025

Introduction: Carica papaya (pawpaw) is commonly used in traditional medicine for its nutritional and therapeutic benefits, yet the effects of its unripe fruit sap on liver function remain poorly studied. This research aimed to assess the hepatotoxic or hepatoprotective propertie...

Open access Research Article 10.9734/ajarr/2025/v19i71080

Hepatoprotective Effects of Monoon longifolium (False Ashoka) Seed Extract against Lead Acetate–Induced Liver Damage in Adult Female Wistar Rats

Uzozie Chikere Ofoego, Onuorah Ifechukwu Paschaline, Mbah Chikodili Adolphus & John Obinna Chukwudike · Journal of Advances in Medical and Pharmaceutical Sciences · 2025

The seed of Monoon longifolium is known to possess antioxidant and hepatoprotective properties. This study investigated the protective effects of its methanolic seed extract (MLSE) against lead acetate-induced liver damage in adult female Wistar rats. Thirty-six rats were randoml...

Open access Research Article 10.9734/jamps/2025/v27i6791

Nephroprotective and Antimalarial Effects of Azadirachta indica and Cymbopogon citratus Ethanolic Leaf Extracts in Plasmodium berghei-Infected Mice

Uzozie Chikere Ofoego, Ese Miracle Bassey, Amarachukwu Ndubuisi Ofoego & Princewill Sopuluchukwu Udodi · Journal of Complementary and Alternative Medical Research · 2025

Malaria remains a major public health burden, especially in developing countries, with rising resistance to conventional antimalarial drugs. This study investigated the nephroprotective and antimalarial effects of ethanolic extracts of Azadirachta indica (EAI) and Cymbopogon citr...

Open access Research Article 10.9734/jocamr/2025/v26i6667

Hepatoprotective Effects of Solanum macrocarpon Leaf Extract against Paraquat-induced Liver Toxicity in Wistar Rats

Uzozie Chikere Ofoego, Nwachukwu Chinecherem Favour, Obinwa Benedict Nzube, Ekwujuru Ezinne Uchechi, Ofoego Amarachukwu Ndubuisi & Ezeagu Darlington Kenechukwu · Journal of Advances in Medicine and Medical Research · 2025

Solanum macrocarpon is a nutrient-rich plant, while Paraquat is a widely used contact herbicide and has been linked to liver damage. This study evaluated the hepatoprotective effects of ethanolic leaf extract of Solanum macrocarpon (ELESM) against paraquat-induced liver toxicity...

Open access Research Article 10.9734/jammr/2025/v37i35763

Ameliorative Effects of a Herbal Drink Jigsimur on Paraquat-induced Nephrotoxicity in Wistar Rats

Chukwuka Victor Chika, Uzozie Chikere Ofoego & Tochukwu Nnamdi Nnama · Asian Journal of Advanced Research and Reports · 2025

Introduction: Paraquat is a widely used but highly toxic herbicide known to induce multi-organ damage, especially nephrotoxicity, through the generation of reactive oxygen species (ROS) and oxidative stress. Jigsimur, a polyherbal preparation derived primarily from Aloe ferox, is...

Open access Research Article 10.9734/ajarr/2025/v19i71108

Modulatory Effects of Telfairia occidentalis Ethanolic Leaf Extract on Monosodium Glutamate–Induced Multi-Organ Toxicity in Experimental Rats

Chukwuebuka Stanley ELEMUO, Kamsiyochukwu Olivia MBONU, Chikodili Adolphus MBAH, Amarachukwu Ndubuisi Ofoego, Chinecherem Rosemary OKEKE, Nora Makuochukwu AGU, EZEAGU, Darlington Kenechukwu & Uzozie Chikere Ofoego · Asian Journal of Research in Medical and Pharmaceutical Sciences · 2026

Background: Monosodium glutamate (MSG) is a commonly used flavour enhancer associated experimentally with oxidative stress and organ injury at high doses. This study evaluated the modulatory effects of an ethanolic leaf extract of Telfairia occidentalis on MSG-induced biochemical...

Open access Research Article 10.9734/ajrimps/2026/v15i3400

Arsenic-induced Multi-organ Toxicity and Oxidative Stress: Protective and Pro-oxidant Effects of Corn Silk Extract in Rats

Chikodili Adolphus MBAH, Ebuka Stephen UDOM, Chukwuebuka Stanley ELEMUO, Miracle Chidinma AKOSA, Ebubechukwu Felix OFFOR, Amarachukwu Ndubuisi Ofoego, Ogochukwu Nancy ONUIGBO & Uzozie Chikere Ofoego · Journal of Complementary and Alternative Medical Research · 2026

Arsenic exposure is associated with oxidative stress and injury to metabolically active organs, including the liver, kidney and pancreas. This study evaluated the modulatory effects of ethanolic corn silk extract on arsenic-induced biochemical, oxidative and histological alterati...

Open access Research Article 10.9734/jocamr/2026/v27i7762