Skip to content
U

Uzoefuna Casmir Chima

Publications (6)

Anti-inflammatory Effect of Plant - Derived Resveratrol in Carrageenan- Induced Inflammatory Model in Wistar Rats

Uzoefuna Casmir Chima, Agu Francis Uchenna, Egharevba Jovita, Ani Celestine Okafor, Ejim Nnamdi Ferdinand, Nnachi Ifenna Salvator, Agbor Joseph Ikenna & Nweke Luke Maduka · Asian Journal of Research in Biochemistry · 2026

Background: Inflammation is a protective biological response to harmful stimuli but may cause tissue damage when excessive or prolonged. Carrageenan-induced inflammation is a widely used experimental model for studying anti-inflammatory agents. Plant-based resveratrol, a natural...

Open access Research Article 10.9734/ajrb/2026/v16i2478

Anti-diarrhea Effect of Loperamide Administration in Acute Castor Oil-induced Diarrhea in Pregnancy and Postnatal Outcome in Wistar Rat

Ani Celestine Okafor, Uzoefuna Casmir Chima, Chinedu Happiness Uzoagulu, Ezinwa Anthony Chijioke, Patani Oghenekparobo Patricia & Nweke Maduka Luke · Journal of Complementary and Alternative Medical Research · 2026

Background: Diarrhea during pregnancy poses significant maternal and fetal risks, particularly when associated with dehydration and electrolyte imbalance. Aim: This study investigates the effects of loperamide on castor oil-induced diarrhea in pregnant Wistar rats and evaluates i...

Open access Research Article 10.9734/jocamr/2026/v27i4751

Anti-Lipidemic and Anti-Glycemic Potential of Lactational Exposure to Flavonoid from Hibiscus sabdariffa in Offspring of Wistar Rats

Nyejirime Young Wike, Ndubuisi Nonso Richards, Esther Ifeyinwa Etu, Uzoefuna Casmir Chima, Patrick Alor, Judith Uzezi Egbo, Akhigbe Agatha Oge, Obianuo Chineta Sussan & Agbor Joseph Ikenna · Journal of Complementary and Alternative Medical Research · 2024

Background and Aim: An individual's growth, organ development, physical makeup, and health are significantly influenced by their nutrition in the early stages of development. Hibiscus sabdariffa have been associated with beneficial effects  on human health. The anti-lipidemic and...

Open access Research Article 10.9734/jocamr/2024/v25i10577

Effect of Co-administration of Aqueous Musa acuminata cavendish and Allium sativium Extracts on Streptozotocin - Induced Type 2 Diabetes on Wistar Rat

Ejim Nnamdi Ferdinand, Ani Celestine Okafor, Onah Emmanuel, Okeke Adaobi Pearl, Uzoefuna Casmir Chima & Nweke Luke Maduka · Asian Journal of Research and Reports in Endocrinology · 2026

This study investigated the effects of Musa acuminata Cavendish and Allium sativum aqueous extracts, both individually and in combination, on streptozotocin-induced type 2 diabetes in Wistar rat. A total of thirty (30) male Wistar rats were used in this study and were divided int...

Open access Research Article 10.9734/ajrre/2026/v9i1129

Effect of Crude Musa acuminata Sap on Doxorubicin Hydrochloride Induced Nephrotoxicity in Wistar Rat

Agu Uchenna Francis, Ani, Celestine Okafor, Ejim Nnamdi Ferdinand, Uzoigwe Jide Uzowulu, Uzoefuna Casmir Chima, Agbor Joseph Ikenna, Ezinwa Anthony Chijioke & Nweke Luke Maduka · Asian Journal of Research in Nephrology · 2026

Background: Nephrotoxicity remains a major clinical challenge, particularly in patients undergoing chemotherapy with agents such as doxorubicin (DOX). Doxorubicin-induced renal damage is largely mediated through oxidative stress, inflammation, and tubular epithelial cell injury,...

Open access Research Article 10.9734/ajrn/2026/v9i1119

Effect of Co-administration of Ascorbic Acid (Vitamin C) and Ethanolic Extract of Thymus vulgaris L. on Lipid Profile and Some Liver Function Parameters in Male Wistar Rats

Ejim Nnamdi Ferdinand, Ani Celestine Okafor, Okeke Pearl Adaobi, Uzoigwe Jide Uzowulu, Ndu, Chidiebere Kingsley, Uzoefuna Casmir Chima & Chinedu Happiness Uzoagulu · Asian Journal of Advanced Research and Reports · 2026

Background: Medicinal plants are used in many countries as an alternative to synthetic drugs. Scientists are now paying attention towards herbal extracts to act as microbial agents due to the rise in bacterial resistance to antibiotics, which has increasingly led to world health...

Open access Research Article 10.9734/ajarr/2026/v20i41348