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Urooj Zafar

Publications (12)

Effectiveness of Metformin and its Combination with Probiotic in Polycystic Ovarian Disease with Hyperprolactinemia: A Randomized Clinical Trial

Urooj Zafar, Syeda Amber Zaidi, Hafiz Syed Muhammad Osama Jafri, Sana Imran, Afreen Bhatty & Fizza Abidi · Journal of Pharmaceutical Research International · 2021

Background: Polycystic ovarian syndrome (PCOS) is an endocrine disorder that predominantly affects women of the reproductive age. Anovulation and abnormal uterine bleeding are caused by hyperprolactinemia, which affects the hypothalamic-pituitary-ovarian axis. Aim: In this study,...

Open access Research Article 10.9734/jpri/2021/v33i47A33013

Altered Thyroid Function amongst the Infertile Insulin Resistant Women with Polycystic Ovarian Syndrome

Urooj Zafar, Aliya Irshad Sani, Hira Ahmed Malik, Aisha Faraz, Rabeea Rizwan & Mariam Muneer · Journal of Pharmaceutical Research International · 2021

Background: Polycystic ovarian syndrome (PCOS) is a hormonal disorder common among women of the child-bearing age. Likewise, women with PCOS are more likely to be obese or overweight, which may be due to their higher Insulin resistance and TSH levels. Aim: The study's objectives...

Open access Research Article 10.9734/jpri/2021/v33i34A31825

Effect of Metformin and Its Combination with Probiotic on Menstrual Irregularity and TSH Levels in Patients with Polycystic Ovarian Syndrome: A Randomized Controlled Trial

Urooj Zafar, Nasima Iqbal, Faizah Mughal, Faiza Quraishi, Ali Nawaz Bijarani & Mariam Muneer · Journal of Pharmaceutical Research International · 2021

Background: Polycystic ovarian syndrome (PCOS), the far most common endocrine disorder among sexually active women. The disease is typically characterized by irregular menstrual cycles and appears to be influenced by associated thyroid dysfunction. Aim: The goal of this research...

Open access Research Article 10.9734/jpri/2021/v33i33A31768

Effectiveness of Probiotics, Metformin and Their Combination Therapy in Ameliorating Dyslipidemia Associated With PCOS

Urooj Zafar, Jahan Ara Hassan, Kauser Ismail, Shanza Agha, Zahida Memon & Shaheen Bhatty · Journal of Pharmaceutical Research International · 2019

Background: Polycystic ovary syndrome (PCOS) is a heterogeneous metabolic disorder affecting women of the child-bearing age. Alteration in lipid profile is one of the troublesome features faced by PCOS patients that need to be treated. Aim: The purpose of this study was to compar...

Open access Research Article 10.9734/jpri/2019/v30i430275

Prevalence of PCOS with Associated Symptoms and Complications at Tertiary Care Hospital of Karachi

Urooj Zafar, Zahida Memon, Kausar Moin, Shanza Agha, Jahan Ara Hassan & Dabeeran Zehra · Journal of Advances in Medicine and Medical Research · 2019

Aim: The aim of this study is to determine the prevalence of PCOS among different gynecological disorders at tertiary care hospital of Karachi and to assess the most frequent presenting complaint with associated complications among them. Study Design: Single-centered cross-sectio...

Open access Research Article 10.9734/jammr/2019/v30i430190

Inhibitory Potential of Combination of Macrolide Antibiotic with Conventional Chemotherapeutic Agent Sorafenib on Growth Rate of Cancer Cell Population

Dabeeran Zehra, Shumaila Usman, Kauser Ismail, Syed Saud Hasan, Urooj Zafar, Syed Faizan Ali Rizvi & Nabila Rasheed · Journal of Pharmaceutical Research International · 2021

Over the past few years great progress has been achieved in anticancer therapy, but development of resistance and unavoidable side effects have incapacitated these fulfilments. Keeping in view this demanding condition, numerous drugs with unique antitumor mechanisms are under inv...

Open access Research Article 10.9734/jpri/2021/v33i47B33124

Prevalence of Adverse Reactions to Different COVID-19 Vaccinations among Karachi Residents

Hira Ahmed Malik, Aisha Faraz, Afreen Bhatty, Tayyaba Mumtaz, Urooj Zafar & Samreen Khurram · Journal of Pharmaceutical Research International · 2021

Background: Coronavirus disease 2019 (COVID-19) pandemic emerged in Karachi and rapidly spread throughout Pakistan Since February 26, 2020.  Objectives: Vaccination is currently one of the most effective COVID-19 eradication approach. The purpose of this study was to gather data...

Open access Research Article 10.9734/jpri/2021/v33i47A33023

Attitude and Practices Regarding Use of Direct Acting Antiviral Agents (DAAs) in the Treatment of Hepatitis C among Health Care Practitioners “A Survey-based Study”

Nadia Saifullah, Dabeeran Zehra, Ambreen Wasim, Samia Saifullah, Urooj Zafar & Akhtar Ali · Journal of Pharmaceutical Research International · 2021

Approximately 3% of the world population has been known to be infected with HCV. Hepatitis C virus is a major etiological factor behind the development of liver diseases such as cirrhosis and hepatocellular carcinoma. Interferon-based therapy has remained as the mainstay treatmen...

Open access Research Article 10.9734/jpri/2021/v33i30B31647

Comparative Analysis of Antidyslipidemic Effects of Fenugreek Seed Extract and Standard Pharmacological Therapy in Diet Induced Animal Model of Dyslipidemia: An Experimental Study

Nisha Zahid, Shehla Shaheen, Zahida Memon, Akhtar Ali, Urooj Zafar & Faiza Agha · Journal of Pharmaceutical Research International · 2020

Objectives: The objective of this study was to compare the antidyslipidemic effects of fenugreek seed extract in comparison to standard drugs used for dyslipidemia in an animal model of dyslipidemia. Methods: It was an experimental study conducted on 42 male, 9 weeks old Wistar a...

Open access Research Article 10.9734/jpri/2020/v32i2230782

Antitumor Potential of Antimicrobials: An Anticipated Armour for Hepatocellular Carcinoma

Dabeeran Zehra, Zahida Memon, Kauser Moin, Shumaila Usman, Urooj Zafar & Nisha Zahid · Journal of Advances in Medicine and Medical Research · 2019

Hepatocellular carcinoma also known as hepatoma is considered as the most common type of primary liver malignancy and is the leading cause of death worldwide. The incidence and mortality is still on the rise despite the drastic progress in early screening tools and new advancemen...

Open access Research Article 10.9734/jammr/2019/v30i730212

Frequency of Different Bacterial Species and their Antibiogram among Patients with Chronic Otitis Media

Mohammad Farooq Bhutta, Ashfaq Hussain, Salman Baig, Asad Ullah, Sarwath Fatimee & Urooj Zafar · Journal of Pharmaceutical Research International · 2021

Aim: To find out the frequency of different bacterial species and their antibiogram among the patients of chronic suppurative otitis media. Study Design: Descriptivecross-sectional. Place and Duration of Study: The study was conducted at the ENT department of Bahawal Victoria hos...

Open access Research Article 10.9734/jpri/2021/v33i30B31657

Frequency of Sensorineural Hearing Loss among Children with Pyogenic Meningitis

Salman Baig, Muhammad Salman Khan, Nasima Iqbal, Tayyaba Mumtaz, Ashfaq Hussain & Urooj Zafar · Journal of Pharmaceutical Research International · 2021

Aim: To find out the frequency of sensorineural hearing loss among children with pyogenic meningitis. Study Design: Cross-sectional. Place and Duration of Study: Study was conducted at Ziauddin university hospital during the period of July 2019 to February 2020. Methodology: Abou...

Open access Research Article 10.9734/jpri/2021/v33i29A31577